Dietary antioxidants and 10-year lung function decline in adults from the ECRHS survey.

Dietary antioxidants and 10-year lung function decline in adults from the ECRHS survey.
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DOI:
10.1183/13993003.02286-2016
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发表时间:
2017-12
期刊:
The European respiratory journal
影响因子:
--
通讯作者:
Jarvis DL
Jarvis DL
中科院分区:
其他
文献类型:
--
作者:
Garcia-Larsen V;Potts JF;Omenaas E;Heinrich J;Svanes C;Garcia-Aymerich J;Burney PG;Jarvis DL

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对来自三个欧洲国家的成年人 10 年来肺功能下降与膳食抗氧化剂之间的关系进行了调查。 2002年,来自欧洲共同体呼吸健康调查(ECRHS)三个参与国的成年人回答了一份调查问卷,并接受了肺活量测定(1秒用力呼气量(FEV1)和用力肺活量(FVC)),10年后重复进行这些检查。通过食物频率问卷(FFQ)在基线估计膳食摄入量。通过多变量分析检查每年肺功能下降(mL)和饮食(三分位数)之间的关联。西蒙斯程序用于控制多重测试。总共包括 680 名个体(基线平均年龄 43.8±6.6  岁)。每三分位数苹果和香蕉摄入量的增加与 FEV1 和 FVC 分别减缓 3.59 mL·year−1 (95% CI 0.40, 7.68) 和 3.69 mL·year−1 (95% CI 0.25, 7.14) 下降相关。番茄摄入量还与 FVC 较慢下降相关(4.5 mL·year−1;95% CI 1.28,8.02)。在进行西蒙斯手术后,只有与番茄摄入量的相关性仍然具有统计学意义。亚组分析表明,苹果、香蕉和番茄的摄入量均与戒烟者用力肺活量较慢下降有关。摄入水果和西红柿可能会延缓成人肺功能的下降,尤其是戒烟者。水果和番茄摄入量越高,肺功能下降速度越慢,尤其是戒烟者 http://ow.ly/5LLv30gK9Bn
The relationship between lung function decline and dietary antioxidants over 10 years in adults from three European countries was investigated. In 2002, adults from three participating countries of the European Community Respiratory Health Survey (ECRHS) answered a questionnaire and underwent spirometry (forced expiratory volume in 1 s (FEV1) and forced vital capacity (FVC)), which were repeated 10 years later. Dietary intake was estimated at baseline with food frequency questionnaires (FFQ). Associations between annual lung function decline (mL) and diet (tertiles) were examined with multivariable analyses. Simes’ procedure was applied to control for multiple testing. A total of 680 individuals (baseline mean age 43.8±6.6 years) were included. A per-tertile increase in apple and banana intake was associated with a 3.59 mL·year−1 (95% CI 0.40, 7.68) and 3.69 mL·year−1 (95% CI 0.25, 7.14) slower decline in FEV1 and FVC, respectively. Tomato intake was also associated with a slower decline in FVC (4.5 mL·year−1; 95% CI 1.28, 8.02). Only the association with tomato intake remained statistically significant after the Simes’ procedure was performed. Subgroup analyses showed that apple, banana and tomato intake were all associated with a slower decline in FVC in ex-smokers. Intake of fruits and tomatoes might delay lung function decline in adults, particularly in ex-smokers. A higher intake of fruits and tomato is associated with a slower lung function decline, particularly in ex-smokers http://ow.ly/5LLv30gK9Bn
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发表时间: 2010-09-01
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