Glucocorticoids, the evolution of the stress-response, and the primate predicament.
Glucocorticoids, the evolution of the stress-response, and the primate predicament.
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DOI：
10.1016/j.ynstr.2021.100320
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发表时间：
2021-05
影响因子：
5
通讯作者：
Sapolsky RM
中科院分区：
文献类型：
--
作者：
Sapolsky RM
肾上腺皮质应激反应在哺乳动物、鸟类、鱼类、爬行动物和两栖动物中非常保守，这表明它在脊椎动物存在的数亿年中一直存在。鉴于自古以来，灵长类动物的社会复杂性已经进化到相对较新的程度，独特的是，生活可以由慢性心理社会压力主导。本文首先回顾了脊椎动物历史上肾上腺皮质的进化。这就产生了一个一致的主题，即在持续的身体压力下，糖皮质激素的保护作用与糖皮质激素分泌过多的不利长期后果之间存在进化权衡；如何解决这种权衡取决于种群、物种和脊椎动物类群的特定生活史策略。这与社会复杂的灵长类动物的肾上腺皮质进化形成鲜明对比，灵长类动物在慢性心理社会压力期间不适应地激活经典的脊椎动物压力反应。这强调了相当独特且持续的选择性力量塑造了包括人类在内的灵长类动物的压力反应。
The adrenocortical stress-response is extraordinarily conserved across mammals, birds, fish, reptiles, and amphibians, suggesting that it has been present during the hundreds of millions of years of vertebrate existence. Given that antiquity, it is relatively recent that primate social complexity has evolved to the point that, uniquely, life can be dominated by chronic psychosocial stress. This paper first reviews adrenocortical evolution during vertebrate history. This produces a consistent theme of there being an evolutionary tradeoff between the protective effects of glucocorticoids during an ongoing physical stressor, versus the adverse long-term consequences of excessive glucocorticoid secretion; how this tradeoff is resolved depends on particular life history strategies of populations, species and vertebrate taxa. This contrasts with adrenocortical evolution in socially complex primates, who mal-adaptively activate the classic vertebrate stress-response during chronic psychosocial stress. This emphasizes the rather unique and ongoing selective forces sculpting the stress-response in primates, including humans.
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影响因子：
3.3
作者：
Haase, Catherine G.;Long, Andrea K.;Gillooly, James F.
通讯作者：
Gillooly, James F.
DOI：
10.1098/rspb.2009.0868
发表时间：
2009-10-07
影响因子：
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作者：
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通讯作者：
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作者：
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通讯作者：
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影响因子：
3
作者：
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通讯作者：
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影响因子：
3.3
作者：
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通讯作者：
Nemeroff, CB