Response of gut microbiota to feed-borne bacteria depends on fish growth rate: a snapshot survey of farmed juvenile Takifugu obscurus.
Response of gut microbiota to feed-borne bacteria depends on fish growth rate: a snapshot survey of farmed juvenile Takifugu obscurus.
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DOI：
10.1111/1751-7915.13741
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发表时间：
2022-03
影响因子：
5.7
通讯作者：
Zhao Z
中科院分区：
文献类型：
--
作者：
Jin X;Chen Z;Shi Y;Gui JF;Zhao Z
这项研究说明了养殖的暗纹东方鲀肠道微生物群中存在明显的多样性-功能关系，并且它暗示了食源性细菌与宿主生长速率之间的强烈相关性。这些结果为河豚和其他经济上重要的鱼类的水产养殖提供了新的见解，以及更好地了解脊椎动物胃肠道中宿主微生物的相互作用。 环境细菌对鱼类肠道菌群有很大的影响，但鱼类从哪里获得肠道共生菌，以及肠道菌群如何对环境细菌的干扰做出反应，目前还知之甚少。通过群落分析和来源追踪的综合分析，我们表明饲料相关细菌可以对养殖河豚的后肠微生物群产生强烈的干扰。因此，在缓慢生长的河豚中观察到肠道微生物群的组成和功能的显著改变，这意味着在来自饲料的细菌干扰下稳定性降低。定量生态学分析表明，在干扰程度较低的情况下，均匀选择和扩散限制对群落稳定性和寄主间的局部变异有很大贡献。当干扰达到峰值时，变量选择导致肠道微生物群内的相互作用增强，从而导致群落不稳定和转移。我们的研究结果强调了饲料和肠道微生物群之间的复杂联系，并强调了在得出微生物群比较分析结论之前解决饲料来源信号的重要性。我们的研究结果提供了一个更深入的了解河豚鱼和其他经济上重要的鱼类水产养殖，并有进一步的影响，以提高理解宿主微生物在脊椎动物胃肠道的相互作用。
This study illustrated a clear diversity‐function relationships in the gut microbiota of cultured obscure puffer Takifugu obscurus, and it has implicated in a strong correlation between feed‐borne bacteria and host growth rate. These results provide a new insight into aquaculture of fugu and other economically important fishes, as well as a better understanding of host‐microbe interactions in the vertebrate gastrointestinal tract. Environmental bacteria have a great impact on fish gut microbiota, yet little is known as to where fish acquire their gut symbionts, and how gut microbiota response to the disturbance from environmental bacteria. Through the integrative analysis by community profiling and source tracking, we show that feed‐associated bacteria can impose a strong disturbance upon the hindgut microbiota of cultured fugu. Consequently, marked alterations in the composition and function of gut microbiota in slow growth fugu were observed, implying a reduced stability upon bacterial disturbance from feed. Moreover, quantitative ecological analyses indicated that homogeneous selection and dispersal limitation largely contribute to the community stability and partial variations among hosts in the context of lower degree of disturbance. While the disturbance peaked, variable selection leads to an augmented interaction within gut microbiota, entailing community unstability and shift. Our findings emphasized the intricate linkage between feed and gut microbiota and highlighted the importance of resolving the feed source signal before the conclusion of comparative analysis of microbiota can be drawn. Our results provide a deeper insight into aquaculture of fugu and other economically important fishes and have further implications for an improved understanding of host–microbe interactions in the vertebrate gastrointestinal tract.
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影响因子：
16.6
作者：
Cazares, Adrian;Moore, Matthew P.;Winstanley, Craig
通讯作者：
Winstanley, Craig
影响因子：
4.6
作者：
Giatsis C;Sipkema D;Smidt H;Heilig H;Benvenuti G;Verreth J;Verdegem M
通讯作者：
Verdegem M
影响因子：
9.8
作者：
Bordenstein SR;Theis KR
通讯作者：
Theis KR
影响因子：
3.4
作者：
Golas, Iwona;Szmyt, Mariusz;Glinska-Lewczuk, Katarzyna
通讯作者：
Glinska-Lewczuk, Katarzyna
影响因子：
5.2
作者：
Dai T;Fuchs BB;Coleman JJ;Prates RA;Astrakas C;St Denis TG;Ribeiro MS;Mylonakis E;Hamblin MR;Tegos GP
通讯作者：
Tegos GP