Mucosal biofilms of Candida albicans.

Mucosal biofilms of Candida albicans.
复制标题

DOI:
10.1016/j.mib.2011.06.001
复制
发表时间:
2011-08
影响因子:
5.4
通讯作者:
Mitchell, Aaron P.
Mitchell, Aaron P.
中科院分区:
生物学2区
文献类型:
--
作者:
Ganguly, Shantanu;Mitchell, Aaron P.

文献摘要

参考文献

被引文献

相似文献

生物膜是在表面上形成并嵌入细胞外基质中的微生物群落。C.白色念珠菌形成由宿主免疫或粘膜生态变化引起的致病性粘膜生物膜。粘液表面居住着许多微生物物种,因此这些生物膜是多微生物的。最近的几项研究已经应用生物膜分析的范例来研究粘膜C。白色念珠菌感染这些研究表明Bcr 1转录因子是C.白念珠菌生物膜形成在不同的条件下,虽然最相关的Bcr1靶基因可以随着生物膜生态位而变化。粘膜生物膜形成的一个重要决定因素是与宿主防御的相互作用。最后,研究了细菌与C.白色念珠菌提供了对赋予多微生物生物膜独特性质的通信机制的深入了解。
Biofilms are microbial communities that form on surfaces and are embedded in an extracellular matrix. C. albicans forms pathogenic mucosal biofilms that are evoked by changes in host immunity or mucosal ecology. Mucosal surfaces are inhabited by many microbial species; hence these biofilms are polymicrobial. Several recent studies have applied paradigms of biofilm analysis to study mucosal C. albicans infections. These studies reveal that the Bcr1 transcription factor is a master regulator of C. albicans biofilm formation under diverse conditions, though the most relevant Bcr1 target genes can vary with the biofilm niche. An important determinant of mucosal biofilm formation is the interaction with host defenses. Finally, studies of interactions between bacterial species and C. albicans provide insight into the communication mechanisms that endow polymicrobial biofilms with unique properties.
DOI: 10.1155/2010/940383
发表时间: 2010
影响因子: 4.6
作者:
Bahri R;Curt S;Saidane-Mosbahi D;Rouabhia M
通讯作者: Rouabhia M
白色念珠菌在阴道粘膜上形成生物膜。
DOI: 10.1099/mic.0.039354-0
发表时间: 2010-12
期刊: Microbiology (Reading, England)
影响因子: --
作者:
Harriott MM;Lilly EA;Rodriguez TE;Fidel PL;Noverr MC
通讯作者: Noverr MC
DOI: 10.1371/journal.ppat.1000752
发表时间: 2010-02-05
期刊: PLoS pathogens
影响因子: 6.7
作者:
Blankenship JR;Fanning S;Hamaker JJ;Mitchell AP
通讯作者: Mitchell AP
DOI: 10.1177/00220345010800031101
发表时间: 2001-03-01
影响因子: 7.6
作者:
Chandra, J;Mukherjee, PK;Ghannoum, MA
通讯作者: Ghannoum, MA
DOI: 10.1038/mi.2009.100
发表时间: 2009-09
期刊: Mucosal immunology
影响因子: 8
作者:
通讯作者: --