A mycorrhiza-associated receptor-like kinase with an ancient origin in the green lineage.

A mycorrhiza-associated receptor-like kinase with an ancient origin in the green lineage.
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DOI:
10.1073/pnas.2105281118
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发表时间:
2021-06-22
影响因子:
11.1
通讯作者:
Paszkowski U
Paszkowski U
中科院分区:
综合性期刊1区
文献类型:
--
作者:
Montero H;Lee T;Pucker B;Ferreras-Garrucho G;Oldroyd G;Brockington SF;Miyao A;Paszkowski U

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受体样激酶(RLK)是细胞信号传导的关键组分。水稻ARBUSCULAR RECEPTOR-LIKE KINASE 1(OsARK 1)是调控丛枝菌根(AM)的一个未定义的RLKs亚家族。我们的系统发育分析表明,ARK 1在种子植物中有一个古老的parpartial,ARK 2。水稻中的单个ark 2和ark 1/ark 2双突变体显示了OsARK 2的非冗余AM共生功能。全球转录组学鉴定了一组由两个RLK共同调控的基因,表明OsARK 1和OsARK 2在共同的途径中协调共生。方舟谱系蛋白在其胞外区具有新鉴定的SP方舟结构域,其在单子叶植物中经历了ARK 1和ARK 2的平行丢失。该蛋白质结构域在链霉菌藻类中具有古老的起源,并定义了另外被忽视的推定细胞表面受体组。
Receptor-like kinases (RLKs) are key cell signaling components. The rice ARBUSCULAR RECEPTOR-LIKE KINASE 1 (OsARK1) regulates the arbuscular mycorrhizal (AM) association postarbuscule development and belongs to an undefined subfamily of RLKs. Our phylogenetic analysis revealed that ARK1 has an ancient paralogue in spermatophytes, ARK2. Single ark2 and ark1/ark2 double mutants in rice showed a nonredundant AM symbiotic function for OsARK2. Global transcriptomics identified a set of genes coregulated by the two RLKs, suggesting that OsARK1 and OsARK2 orchestrate symbiosis in a common pathway. ARK lineage proteins harbor a newly identified SPARK domain in their extracellular regions, which underwent parallel losses in ARK1 and ARK2 in monocots. This protein domain has ancient origins in streptophyte algae and defines additional overlooked groups of putative cell surface receptors.
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