Organophosphate pesticide exposure and work in pome fruit: evidence for the take-home pesticide pathway.
Organophosphate pesticide exposure and work in pome fruit: evidence for the take-home pesticide pathway.
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DOI：
10.1289/ehp.8620
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发表时间：
2006-07
影响因子：
10.4
通讯作者：
Faustman EM
中科院分区：
文献类型：
--
作者：
Coronado GD;Vigoren EM;Thompson B;Griffith WC;Faustman EM
有机磷（OP）杀虫剂在美国被广泛使用，农场工人有长期接触的风险。在东部华盛顿州的24个社区和劳改营的218名农场工人的样本中，我们研究了农业作物和OP农药代谢物浓度之间的关联成年农场工人和他们的孩子的尿样和OP农药残留的房屋和车辆灰尘样本。常见的作物有苹果（71.6%）、樱桃（59.6%）、梨（37.2%）、葡萄（27.1%）、啤酒花（22.9%）和桃子（12.4%）。作物分为两大类：仁果类（苹果和梨）和非仁果类。在梨果中工作的农场工人尿液中二甲基农药代谢物的浓度显着较高，家中和车辆中的azinander-methyl浓度高于不从事这些作物的工人。在梨果工人中，那些同时在苹果和梨上工作的人比那些在单一梨果上工作的人有更高的尿液代谢物浓度和灰尘中的农药残留浓度。与非梨果工人相比，梨果工人家庭中的儿童尿二甲基代谢物浓度更高。成人尿液浓度与溶剂和室内灰尘中的甲基阿齐灵浓度均显示出显著相关性，儿童尿液浓度与成人尿液浓度和室内灰尘中的甲基阿齐灵浓度显著相关。研究结果为农药暴露的回家途径提供了支持，并显示了农药暴露措施与农场工人种植的梨果作物数量之间的关联。
Organophosphate (OP) pesticides are commonly used in the United States, and farmworkers are at risk for chronic exposure. Using a sample of 218 farmworkers in 24 communities and labor camps in eastern Washington State, we examined the association between agricultural crop and OP pesticide metabolite concentrations in urine samples of adult farmworkers and their children and OP pesticide residues in house and vehicle dust samples. Commonly reported crops were apples (71.6%), cherries (59.6%), pears (37.2%), grapes (27.1%), hops (22.9%), and peaches (12.4%). Crops were grouped into two main categories: pome fruits (apples and pears) and non-pome fruits. Farmworkers who worked in the pome fruits had significantly higher concentrations of dimethyl pesticide metabolites in their urine and elevated azinphos-methyl concentrations in their homes and vehicles than workers who did not work in these crops. Among pome-fruit workers, those who worked in both apples and pears had higher urinary metabolites concentrations and pesticide residue concentrations in dust than did those who worked in a single pome fruit. Children living in households with pome-fruit workers were found to have higher concentrations of urinary dimethyl metabolites than did children of non-pome-fruit workers. Adult urinary concentrations showed significant correlations with both the vehicle and house-dust azinphos-methyl concentrations, and child urinary concentrations were correlated significantly with adult urinary concentrations and with the house-dust azinphos-methyl concentration. The results provide support for the take-home pathway of pesticide exposure and show an association between measures of pesticide exposure and the number of pome-fruit crops worked by farmworkers.
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影响因子：
10.4
作者：
Fenske RA;Lu C;Barr D;Needham L
通讯作者：
Needham L
居住在农业社区的儿童尿液中有机磷酸盐农药代谢物的变化。
影响因子：
10.4
作者：
Lambert, William E;Lasarev, Michael;Muniz, Juan;Scherer, Jennifer;Rothlein, Joan;Santana, Juanita;McCauley, Linda
通讯作者：
McCauley, Linda
影响因子：
10.4
作者：
Coronado GD;Thompson B;Strong L;Griffith WC;Islas I
通讯作者：
Islas I
影响因子：
5
作者：
Fritschi, L;Benke, G;Armstrong, BK
通讯作者：
Armstrong, BK
影响因子：
3.5
作者：
MCCONNELL, R;KEIFER, M;ROSENSTOCK, L
通讯作者：
ROSENSTOCK, L