Plasticity of population coding in primary sensory cortex.

Plasticity of population coding in primary sensory cortex.
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DOI:
10.1016/j.conb.2018.04.029
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发表时间:
2018-12
影响因子:
5.7
通讯作者:
Feldman DE
Feldman DE
中科院分区:
医学2区
文献类型:
--
作者:
LeMessurier AM;Feldman DE

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That experience shapes sensory tuning in primary sensory cortex is well understood. But effective neural population codes depend on more than just sensory tuning. Recent population imaging and recording studies have characterized population codes in sensory cortex, and tracked how they change with sensory manipulations and training on perceptual learning tasks. These studies confirm sensory tuning changes, but also reveal other features of plasticity, including sensory gain modulation, restructuring of firing correlations, and differential routing of information to output pathways. Unexpectedly strong day-to-day variation exists in single-neuron sensory tuning, which stabilizes during learning. These are novel dimensions of plasticity in sensory cortex, which refine population codes during learning, but whose mechanisms are unknown.
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