Suppression of allatotropin simulates reproductive diapause in the mosquito Culex pipiens.
Suppression of allatotropin simulates reproductive diapause in the mosquito Culex pipiens.
复制标题
抑制尿素可模拟淡色库蚊的生殖滞育。
DOI：
10.1016/j.jinsphys.2014.03.005
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发表时间：
2014-05
影响因子：
2.2
通讯作者：
Sim C
中科院分区：
文献类型：
--
作者：
Kang DS;Denlinger DL;Sim C
保幼激素（JH）的停止产生是一个关键的内分泌事件，停止卵巢发育，从而启动滞育的雌性库蚊，尖音库蚊。关闭内分泌活动的咽侧体（CA），源的JH，表现在较小的尺寸CA在短日照（滞育）下饲养的女性相比，那些饲养在长日照（nondiapause），以及在低表达的mRNA编码allatotropin，神经肽，促进JH生物合成的CA。在C. pipiens，但只有allatotropin的表达水平在两种类型的女性不同。敲低allatotropin mRNA使用RNA干扰的女性编程nondiapause导致卵巢发育停止类似滞育。这种发展中的停滞可以通过应用JH来逆转。因此，我们的研究结果表明，抑制allatotropin是一个关键环节，在调节关闭的CA滞育期间。
The cessation of juvenile hormone (JH) production is a key endocrine event that halts ovarian development and hence initiates diapause in females of the mosquito, Culex pipiens. The shutdown in endocrine activity of the corpora allata (CA), the source of JH, was manifested in the smaller size of CA in females reared under short daylengths (diapause) compared to those reared under long daylengths (nondiapause), as well as in low expression of the mRNA encoding allatotropin, the neuropeptide that promotes JH biosynthesis in the CA. Genes encoding both allatotropin and allatostatin were identified in C. pipiens, but only expression levels of allatotropin differed in the two types of females. Knockdown of allatotropin mRNA using RNA interference in females programmed for nondiapause resulted in a cessation of ovarian development akin to diapause. This arrest in development could be reversed with an application of JH. Our results thus suggest that suppression of allatotropin is a critical link in regulating the shutdown of the CA during diapause.
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胰岛素信号传导和昆虫滞育的调节。
影响因子：
4
作者：
Sim C;Denlinger DL
通讯作者：
Denlinger DL
DOI：
10.1073/pnas.0507958102
发表时间：
2005-11-01
影响因子：
11.1
作者：
Robich, RM;Denlinger, DL
通讯作者：
Denlinger, DL
影响因子：
2.2
作者：
Hernandez-Martinez, Salvador;Mayoral, Jaime G.;Noriega, Fernando G.
通讯作者：
Noriega, Fernando G.
影响因子：
--
作者：
Li, YP;Hernandez-Martinez, S;Noriega, FG
通讯作者：
Noriega, FG
影响因子：
56.9
作者：
KATAOKA, H;TOSCHI, A;KRAMER, SJ
通讯作者：
KRAMER, SJ