Electronic Cigarette Use during Pregnancy: Is It Harmful?
Electronic Cigarette Use during Pregnancy: Is It Harmful?
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DOI：
10.3390/toxics11030278
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发表时间：
2023-03-18
期刊：
影响因子：
4.6
通讯作者：
Sinkey RG
中科院分区：
文献类型：
--
作者：
Vilcassim MJR;Stowe S;Majumder R;Subramaniam A;Sinkey RG
虽然近年来可燃香烟的吸烟率有所下降，但替代烟草产品的使用，特别是电子烟的使用（“vaping”），在年轻人中有所增加。最近的研究表明，怀孕期间的vaping正在上升，可能是因为人们认为它是可燃香烟吸烟的更安全的替代品。然而，电子烟气溶胶可能含有几种更新的潜在有毒化合物，包括一些已知的可能对母亲和胎儿产生不利影响的发育毒物。然而，很少有研究检查怀孕期间vaping的影响。虽然怀孕期间吸烟的不良围产期结果已经得到了很好的证实，但与怀孕期间吸入雾化气溶胶相关的具体风险需要更多的研究。在这篇文章中，我们讨论了关于怀孕期间吸烟风险的现有证据和知识差距。研究与电子烟相关的全身暴露及其影响的研究（即，生物标志物分析）以及孕产妇和新生儿临床健康结果，以得出更有力的结论。我们特别强调需要超越与香烟的比较研究，并倡导客观评估电子烟和其他替代烟草产品安全性的研究。
Although combustible cigarette smoking rates have declined in recent years, alternative tobacco product use, particularly electronic cigarette use (“vaping”), has increased among young adults. Recent studies indicate that vaping during pregnancy is on the rise, possibly due to the perception that it is a safer alternative to combustible cigarette smoking. However, e-cigarette aerosols may contain several newer, potentially toxic compounds, including some known developmental toxicants that may adversely impact both the mother and the fetus. However, there is paucity of studies that have examined the effects of vaping during pregnancy. While the adverse perinatal outcomes of cigarette smoking during pregnancy are well established, the specific risks associated with inhaling vaping aerosols during pregnancy requires more research. In this article, we discuss the existing evidence and knowledge gaps on the risks of vaping during pregnancy. Studies that investigate vaping-associated systemic exposure and its effects (i.e., biomarker analyses) and maternal and neonatal clinical health outcomes are needed to reach more robust conclusions. We particularly emphasize the need to go beyond comparative studies with cigarettes, and advocate for research that objectively evaluates the safety of e-cigarettes and other alternative tobacco products.
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影响因子：
3.7
作者：
Abraham M;Alramadhan S;Iniguez C;Duijts L;Jaddoe VW;Den Dekker HT;Crozier S;Godfrey KM;Hindmarsh P;Vik T;Jacobsen GW;Hanke W;Sobala W;Devereux G;Turner S
通讯作者：
Turner S
影响因子：
4.6
作者：
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通讯作者：
Paolini M
DOI：
10.1164/rccm.201912-2332ws
发表时间：
2020-09-15
影响因子：
24.7
作者：
Alexander, Laura E. Crotty;Ware, Lorraine B.;Tarran, Robert
通讯作者：
Tarran, Robert
影响因子：
3.2
作者：
Bhandari, Naleen Raj;Day, Kanesha D.;Ragland, Denise
通讯作者：
Ragland, Denise
DOI：
10.1038/nrcardio.2017.36
发表时间：
2017-08
期刊：
Nature reviews. Cardiology
影响因子：
--
作者：
Benowitz NL;Fraiman JB
通讯作者：
Fraiman JB