Molecular imaging of inflammation and carcinogenesis.

Molecular imaging of inflammation and carcinogenesis.
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炎症和癌变的分子成像。

DOI:
10.1158/1940-6207.capr-11-0418
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发表时间:
2011
期刊:
Cancer prevention research (Philadelphia, Pa.)
影响因子:
--
通讯作者:
Contag,ChristopherH
Contag,ChristopherH
中科院分区:
--
文献类型:
--
作者:
Ostrov,DavidA;Contag,ChristopherH

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Development of imaging agents that can be used broadly for early detection of neoplasia at various tissue sites and at various stages of disease and that also can assess states of minimal residual disease would have tremendous utility in the diagnosis and management of cancer. In a series of articles culminating with a report in this issue of the journal (beginning on page 1536), Uddin and colleagues show their ability tosystemicallytarget the enzyme COX-2 with imaging probes that will serve as agents for early detection, risk assessment, prognosis, and intervention outcome measures. These probes will enable the detection and localization of regions of inflammation and a wide variety of premalignant lesions and cancers, with utility in monitoring the effects of cancer prevention and therapy.Cancer Prev Res; 4(10); 1523–6. ©2011 AACR.
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