Pharmacologic management of cancer pain in rural Minnesota.

Pharmacologic management of cancer pain in rural Minnesota.
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明尼苏达州农村癌症疼痛的药物治疗。

DOI:
10.1016/s0885-3924(96)00179-0
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发表时间:
1996
影响因子:
4.7
通讯作者:
Elliott,TE
Elliott,TE
中科院分区:
医学2区
文献类型:
--
作者:
Lichtblau,L;Belgrade,M;Auld,R;Elliott,TE

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在明尼苏达州的六个社区评估了癌痛镇痛药物的使用情况。在我们的调查中,癌症患者主要由家庭医生治疗。大约70%的患者接受了一种或多种镇痛药; 84%的患者接受了非甾体类镇痛药,73%的患者接受了阿片类药物。大多数服用抗抑郁药的患者接受的药物剂量低于最大推荐剂量。治疗癌症疼痛最常见的阿片类药物是口服吗啡。大约40%接受阿片类药物治疗的患者仅在需要时服用药物;其余患者全天候服用药物,有或没有额外的阿片类药物用于突破性疼痛。接受镇痛药的患者中,只有14%接受了辅助镇痛药,只有13%接受了非镇痛药辅助治疗。这些社区的镇痛药使用模式与公认的癌痛管理原则一致:自由使用阿片类药物,使用口服吗啡作为主要药物,避免哌替啶和阿片类激动剂/拮抗剂。
Use of analgesic medications for cancer pain was assessed in six Minnesota communities. In our survey, cancer patients were treated primarily by family practice physicians. Approximately 70% were given one or more analgesics; 84% received a nonsteroidal antiinflammatory drug and 73% received an opioid. Most patients given an antiinflammatory drug received less than the maximal recommended dose for the drug. The most common opioid for cancer pain was oral morphine. Approximately 40% of the patients treated with opioids took the drug only when needed; the remainder took the drug around-the-clock, with or without additional opioids for breakthrough pain. Only 14% of patients who received analgesics received a coanalgesic and only 13% received a nonanalgesic adjuvant. The patterns of analgesic use in these communities corresponded well with accepted principles of cancer pain management: liberal use of opioids, use of oral morphine as the predominant agent, and avoidance of meperidine and opioid agonist/antagonist.
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