Interventions to Reduce Risk for Pathogen Spillover and Early Disease Spread to Prevent Outbreaks, Epidemics, and Pandemics.

Interventions to Reduce Risk for Pathogen Spillover and Early Disease Spread to Prevent Outbreaks, Epidemics, and Pandemics.
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降低病原体溢出和早期疾病传播风险的干预措施,以预防暴发、流行病和大流行。

DOI:
10.3201/eid2903.221079
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发表时间:
2023-03
影响因子:
11.8
通讯作者:
Epstein, Jonathan H.
Epstein, Jonathan H.
中科院分区:
医学2区
文献类型:
--
作者:
Vora, Neil M.;Hannah, Lee;Walzer, Chris;Vale, Mariana M.;Lieberman, Susan;Emerson, Ashley;Jennings, Jonathan;Alders, Robyn;Bonds, Matthew H.;Evans, Jo;Chilukuri, Bhavana;Cook, Sonila;Sizer, Nigel C.;Epstein, Jonathan H.

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引起人类大多数新发传染病的病原体起源于动物,特别是野生动物,然后蔓延到人类身上。由于土地利用变化、畜牧业、活体野生动物市场和贸易等活动,人类和家畜接触野生动物的频率不断增加,为病原体外溢创造了越来越多的机会。然而,通过停止热带和亚热带森林的砍伐和退化、改善新兴传染病热点社区的健康和经济安全、加强畜牧业的生物安全、关闭或严格监管野生动物市场和贸易以及扩大病原体监测,可以降低病原体溢出和早期疾病在家畜和人类中传播的风险。我们总结了关于如何实现这些目标以预防疫情、流行病和大流行的专家意见。
The pathogens that cause most emerging infectious diseases in humans originate in animals, particularly wildlife, and then spill over into humans. The accelerating frequency with which humans and domestic animals encounter wildlife because of activities such as land-use change, animal husbandry, and markets and trade in live wildlife has created growing opportunities for pathogen spillover. The risk of pathogen spillover and early disease spread among domestic animals and humans, however, can be reduced by stopping the clearing and degradation of tropical and subtropical forests, improving health and economic security of communities living in emerging infectious disease hotspots, enhancing biosecurity in animal husbandry, shutting down or strictly regulating wildlife markets and trade, and expanding pathogen surveillance. We summarize expert opinions on how to implement these goals to prevent outbreaks, epidemics, and pandemics.
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