Widespread and Opponent fMRI Signals Represent Sound Location in Macaque Auditory Cortex.

Widespread and Opponent fMRI Signals Represent Sound Location in Macaque Auditory Cortex.
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DOI:
10.1016/j.neuron.2017.01.013
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发表时间:
2017-02-22
期刊:
影响因子:
16.2
通讯作者:
Rauschecker JP
Rauschecker JP
中科院分区:
医学1区
文献类型:
--
作者:
Ortiz-Rios M;Azevedo FAC;Kuśmierek P;Balla DZ;Munk MH;Keliris GA;Logothetis NK;Rauschecker JP

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在灵长类动物中,后部听觉皮质区域被认为是处理空间信息的背部听觉通路的一部分。但后部(和其他)听觉区域如何代表声学空间仍是一个有争议的问题。在这里,我们提供了基于猕猴功能磁共振成像(FMRI)的新证据,表明空间主要由分布式半场编码表示,而不是由局部空间地形表示。皮层和皮质下区域的半视野调谐来自对侧半球的激活和去激活模式,这取决于耳间延迟线索的可用性。重要的是,这些相反的信号允许后部区域的反应以类似于半场编码表示的方式来分隔空间。综上所述,我们的结果调和了看似矛盾的观点,表明空间的表征严格遵循半视野编码,并表明灵长类动物的后背空间专一性可能来自这种编码形式。
In primates, posterior auditory cortical areas are thought to be part of a dorsal auditory pathway that processes spatial information. But how posterior (and other) auditory areas represent acoustic space remains a matter of debate. Here we provide new evidence based on functional magnetic resonance imaging (fMRI) of the macaque indicating that space is predominantly represented by a distributed hemi-field code rather than by a local spatial topography. Hemifield tuning in cortical and subcortical regions emerges from an opponent hemispheric pattern of activation and deactivation that depends on the availability of interaural delay cues. Importantly, these opponent signals allow responses in posterior regions to segregate space similarly to a hemifield code representation. Taken together, our results reconcile seemingly contradictory views by showing that the representation of space follows closely a hemifield code and suggest that enhanced posterior-dorsal spatial specificity in primates might emerge from this form of coding.
颞平面中声音位置(方位角)的对手编码对于声级变化具有鲁棒性。
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