Active and passive smoking and fecundability in Danish pregnancy planners.
Active and passive smoking and fecundability in Danish pregnancy planners.
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DOI：
10.1016/j.fertnstert.2014.03.018
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发表时间：
2014-07
影响因子：
6.7
通讯作者：
Wise, Lauren A.
中科院分区：
文献类型：
--
作者：
Radin, Rose G.;Hatch, Elizabeth E.;Rothman, Kenneth J.;Mikkelsen, Ellen M.;Sorensen, Henrik Toft;Riis, Anders H.;Wise, Lauren A.
调查生育能力与主动吸烟、戒烟时间和被动吸烟的关系程度。前瞻性队列研究。丹麦,2007 - 2011。3773名18-40岁女性计划生育者。没有。自我报告的怀孕。使用比例概率模型估计受精率（FR）和95%置信区间（CI），该模型调整了月经周期风险和潜在混杂因素。在当前吸烟者中，与从不吸烟者相比，吸烟时间≥10年与生育能力降低相关（FR=0.85, 95% CI: 0.72-1.00）。吸烟≥10包年的前吸烟者无论何时戒烟，生育能力都降低（1-1.9年FR=0.83, 95% CI: 0.54-1.27；≥2年FR=0.73, 95% CI: 0.53-1.02）。在从不吸烟者中，早期被动吸烟的风险系数为1.04 (95% CI: 0.89-1.21)，成年被动吸烟的风险系数为0.92 （95% CI: 0.82-1.03）。在丹麦的怀孕计划者中，长期接触主动吸烟与现在和以前吸烟者的延迟受孕有关。戒烟后的时间和被动吸烟与生育能力没有明显的关系。
To investigate the extent to which fecundability is associated with active smoking, time since smoking cessation, and passive smoking. Prospective cohort study. Denmark, 2007–2011. 3,773 female pregnancy planners aged 18–40 years. None. Self-reported pregnancy. Fecundability ratios (FR) and 95% confidence intervals (CI) were estimated using a proportional probabilities model that adjusted for menstrual cycle at risk and potential confounders. Among current smokers, smoking duration ≥10 years was associated with reduced fecundability compared with never smokers (FR=0.85, 95% CI: 0.72–1.00). Former smokers who had smoked ≥10 pack-years had reduced fecundability regardless of when they quit smoking (1–1.9 years FR=0.83, 95% CI: 0.54–1.27; ≥2 years FR=0.73, 95% CI: 0.53–1.02). Among never smokers, the FRs were 1.04 (95% CI: 0.89–1.21) for passive smoking in early life and 0.92 (95% CI: 0.82–1.03) for passive smoking in adulthood. Among Danish pregnancy planners, cumulative exposure to active cigarette smoking was associated with delayed conception among current and former smokers. Time since smoking cessation and passive smoking were not appreciably associated with fecundability.
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影响因子：
6.1
作者：
Benedict, Merle D.;Missmer, Stacey A.;Meeker, John D.
通讯作者：
Meeker, John D.
影响因子：
6.7
作者：
Hull, MGR;North, K;Ford, WCL
通讯作者：
Ford, WCL
影响因子：
7.7
作者：
DEMOUZON, J;SPIRA, A;SCHWARTZ, D
通讯作者：
SCHWARTZ, D
影响因子：
5.4
作者：
Cooper, GS;Sandler, DP;Bohlig, M
通讯作者：
Bohlig, M
影响因子：
5.6
作者：
Joesoef, M R;Beral, V;Cramer, D W
通讯作者：
Cramer, D W