Multishot PROPELLER for high-field preclinical MRI.
Multishot PROPELLER for high-field preclinical MRI.
复制标题
用于高场强临床前磁共振成像的多光点 PROPELLER。
DOI:
10.1002/mrm.22376
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发表时间:
2010-07
影响因子:
3.3
通讯作者:
Johnson, G. Allan
中科院分区:
文献类型:
--
作者:
Pandit, Prachi;Qi, Yi;Story, Jennifer;King, Kevin F.;Johnson, G. Allan
With the development of numerous mouse models of cancer, there is a tremendous need for an appropriate imaging technique to study the disease evolution. High-field T2-weighted imaging using PROPELLER MRI meets this need. The 2-shot PROPELLER technique presented here, provides (a) high spatial resolution, (b) high contrast resolution, and (c) rapid and non-invasive imaging, which enables high-throughput, longitudinal studies in free-breathing mice. Unique data collection and reconstruction makes this method robust against motion artifacts. The 2-shot modification introduced here, retains more high-frequency information and provides higher SNR than conventional single-shot PROPELLER, making this sequence feasible at high-fields, where signal loss is rapid. Results are shown in a liver metastases model to demonstrate the utility of this technique in one of the more challenging regions of the mouse, which is the abdomen.
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影响因子:
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作者:
Inderbitzin, Daniel;Stoupis, Christoforos;Candinas, Daniel
通讯作者:
Candinas, Daniel
影响因子:
3.3
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Maï, W;Badea, CT;Johnson, GA
通讯作者:
Johnson, GA
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Howles, Gabriel P.;Nouls, John C.;Johnson, G. Allan
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Johnson, G. Allan
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通讯作者:
Sadek, AG
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通讯作者:
Clarke, K