Ciliary control of adipocyte progenitor cell fate regulates energy storage.
Ciliary control of adipocyte progenitor cell fate regulates energy storage.
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DOI:
10.3389/fcell.2022.1083372
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发表时间:
2022
影响因子:
5.5
通讯作者:
中科院分区:
文献类型:
--
作者:
The primary cilium is a cellular sensory organelle found in most cells in our body. This includes adipocyte progenitor cells in our adipose tissue, a complex organ involved in energy storage, endocrine signaling, and thermogenesis. Numerous studies have shown that the primary cilium plays a critical role in directing the cell fate of adipocyte progenitor cells in multiple adipose tissue types. Accordingly, diseases with dysfunctional cilia called ciliopathies have a broad range of clinical manifestations, including obesity and diabetes. This review summarizes our current understanding of how the primary cilium regulates adipocyte progenitor cell fate in multiple contexts and illustrates the importance of the primary cilium in regulating energy storage and adipose tissue function.
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影响因子:
4.3
作者:
Cinti S
通讯作者:
Cinti S
影响因子:
3.7
作者:
Baglioni S;Cantini G;Poli G;Francalanci M;Squecco R;Di Franco A;Borgogni E;Frontera S;Nesi G;Liotta F;Lucchese M;Perigli G;Francini F;Forti G;Serio M;Luconi M
通讯作者:
Luconi M
DOI:
10.1242/dev.002642
发表时间:
2007-06
期刊:
Development (Cambridge, England)
影响因子:
--
作者:
Billon N;Iannarelli P;Monteiro MC;Glavieux-Pardanaud C;Richardson WD;Kessaris N;Dani C;Dupin E
通讯作者:
Dupin E
影响因子:
3.6
作者:
Cypess AM;Kahn CR
通讯作者:
Kahn CR
DOI:
10.1007/978-1-4939-6820-6_7
发表时间:
2017-01-01
期刊:
THERMOGENIC FAT
影响因子:
--
作者:
Baker, Nicki A.;Muir, Lindsey A.;O'Rourke, Robert W.
通讯作者:
O'Rourke, Robert W.