The Limbic-Prefrontal Network Modulated by Electroacupuncture at CV4 and CV12.
The Limbic-Prefrontal Network Modulated by Electroacupuncture at CV4 and CV12.
复制标题
DOI：
10.1155/2012/515893
复制
发表时间：
2012
期刊：
影响因子：
--
通讯作者：
Zhu B
中科院分区：
文献类型：
--
作者：
Fang J;Wang X;Liu H;Wang Y;Zhou K;Hong Y;Liu J;Wang L;Xue C;Song M;Liu B;Zhu B
功能磁共振成像研究表明，针刺可引起脑网络的血流动力学变化。其中许多研究集中在特定的穴位是否可以激活特定的大脑区域，并且通常仅限于四肢穴位的手动针灸。本研究通过电针腹部正中穴位，观察针刺对脑功能网络的调制作用。刺激21名健康志愿者的关元穴和中脘穴。针刺感觉，大脑激活和功能连接进行了研究。我们发现，在CV 4和CV12，电针使边缘-前额叶功能网络失活。更重要的是，局部功能连接在EA刺激期间发生了显着变化，并且这种变化在刺激后的一段时间内持续存在。虽然存在微小的差异，这两个穴位同样调制边缘-前额叶功能网络，这是重叠的功能电路与情绪和认知调节。
fMRI studies showed that acupuncture could induce hemodynamic changes in brain networks. Many of these studies focused on whether specific acupoints could activate specific brain regions and were often limited to manual acupuncture at acupoints on the limbs. In this fMRI study, we investigated acupuncture's modulation effects on brain functional networks by electroacupuncture (EA) at acupoints on the midline of abdomen. Acupoints Guanyuan (CV4) and Zhongwan (CV12) were stimulated in 21 healthy volunteers. The needling sensations, brain activation, and functional connectivity were studied. We found that the limbic-prefrontal functional network was deactivated by EA at CV4 and CV12. More importantly, the local functional connectivity was significantly changed during EA stimulation, and the change persisted during the period after the stimulation. Although minor differences existed, both acupoints similarly modulated the limbic-prefrontal functional network, which is overlapped with the functional circuits associated with emotional and cognitive regulation.
登录
查看更多内容
DOI：
10.1073/pnas.0504136102
发表时间：
2005-07-05
影响因子：
11.1
作者：
Fox, MD;Snyder, AZ;Raichle, ME
通讯作者：
Raichle, ME
影响因子：
2.5
作者：
Coghill, RC;Sang, CN;Iadarola, MJ
通讯作者：
Iadarola, MJ
影响因子：
4.8
作者：
Li, G;Liu, HL;Yang, ES
通讯作者：
Yang, ES
DOI：
10.1176/appi.neuropsych.19.3.274
发表时间：
2007-06-01
影响因子：
2.9
作者：
Anand, Amit;Li, Yu;Lowe, Mark J.
通讯作者：
Lowe, Mark J.
影响因子：
5.3
作者：
Davis, KD;Taylor, KS;Lozano, AM
通讯作者：
Lozano, AM