Activation of Person Knowledge in Medial Prefrontal Cortex during the Encoding of New Lifelike Events.
Activation of Person Knowledge in Medial Prefrontal Cortex during the Encoding of New Lifelike Events.
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DOI：
10.1093/cercor/bhab027
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发表时间：
2021-06-10
期刊：
影响因子：
--
通讯作者：
Bird CM
中科院分区：
文献类型：
--
作者：
Raykov PP;Keidel JL;Oakhill J;Bird CM
我们对人的了解可以帮助我们预测他们在特定情况下的行为，并解释他们的行为。在这项研究中，我们调查的认知和神经的影响，人的知识的编码和检索的新的生活一样的事件。健康的人类参与者在一周内通过观看两部情景喜剧中的一部的6集来学习两个角色，这两部情景喜剧都以一对年轻夫妇为中心。在扫描仪中，他们观看，然后默默地回忆起两个节目中的20个新场景，这些场景都设置在陌生的地点：10个来自他们训练过的节目，10个来自未经训练的节目。在扫描之后，参与者对训练节目中的场景的识别记忆更好。在回忆过程中，观看视频时大脑活动的功能性磁共振成像（fMRI）模式得以恢复，但这种效果并没有受到训练的调节。然而，当观看涉及熟悉人物的新事件时，人的知识提高了内侧前额叶皮层（MPFC）活动的fMRI模式的相似性。我们的研究结果确定了MPFC的作用，在编码过程中的示意性的人的知识的编码，逼真的事件。
Our knowledge about people can help us predict how they will behave in particular situations and interpret their actions. In this study, we investigated the cognitive and neural effects of person knowledge on the encoding and retrieval of novel life-like events. Healthy human participants learnt about two characters over a week by watching 6 episodes of one of two situation comedies, which were both centered on a young couple. In the scanner, they watched and then silently recalled 20 new scenes from both shows that were all set in unfamiliar locations: 10 from their trained show and 10 from the untrained show. After scanning, participants’ recognition memory was better for scenes from the trained show. The functional magnetic resonance imaging (fMRI) patterns of brain activity when watching the videos were reinstated during recall, but this effect was not modulated by training. However, person knowledge boosted the similarity in fMRI patterns of activity in the medial prefrontal cortex (MPFC) when watching the new events involving familiar characters. Our findings identify a role for the MPFC in the representation of schematic person knowledge during the encoding of novel, lifelike events.
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影响因子：
16.6
作者：
Horner AJ;Bisby JA;Bush D;Lin WJ;Burgess N
通讯作者：
Burgess N
DOI：
10.1037/0278-7393.3.4.428
发表时间：
1977-01-01
期刊：
JOURNAL OF EXPERIMENTAL PSYCHOLOGY-HUMAN LEARNING AND MEMORY
影响因子：
--
作者：
DOOLING, DJ;CHRISTIAANSEN, RE
通讯作者：
CHRISTIAANSEN, RE
影响因子：
5.7
作者：
Diedrichsen, J;Shadmehr, R
通讯作者：
Shadmehr, R
影响因子：
5.3
作者：
Bird, Chris M.;Keidel, James L.;Burgess, Neil
通讯作者：
Burgess, Neil
影响因子：
5.7
作者：
Elfgren, C;van Westen, D;Fransson, P
通讯作者：
Fransson, P