Marine polysaccharides from algae with potential biomedical applications.

Marine polysaccharides from algae with potential biomedical applications.
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DOI:
10.3390/md13052967
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发表时间:
2015-05-15
期刊:
影响因子:
5.4
通讯作者:
de Morais RM
de Morais RM
中科院分区:
医学2区
文献类型:
--
作者:
de Jesus Raposo MF;de Morais AM;de Morais RM

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目前的趋势是生物活性天然产品在各种行业中的应用,如制药,生物医学,化妆品和食品。这在一定程度上强调了对海洋生物的研究,包括大型藻类和微型藻类等。海洋多糖是一类重要的生物化学物质,具有抗凝血、抗血栓、免疫调节、抗肿瘤、预防癌症、降血脂、降血糖、抗生素、抗炎、抗氧化等作用,是一类具有广泛应用前景的生物活性物质和生物材料。它们的特性主要是由于它们的结构和物理化学特性,这取决于它们产生的生物体。在生物医学领域,来自藻类的多糖可用于控制药物输送、伤口管理和再生医学。本文就海藻多糖在生物医学中的应用作一综述。
There is a current tendency towards bioactive natural products with applications in various industries, such as pharmaceutical, biomedical, cosmetics and food. This has put some emphasis in research on marine organisms, including macroalgae and microalgae, among others. Polysaccharides with marine origin constitute one type of these biochemical compounds that have already proved to have several important properties, such as anticoagulant and/or antithrombotic, immunomodulatory ability, antitumor and cancer preventive, antilipidaemic and hypoglycaemic, antibiotics and anti-inflammatory and antioxidant, making them promising bioactive products and biomaterials with a wide range of applications. Their properties are mainly due to their structure and physicochemical characteristics, which depend on the organism they are produced by. In the biomedical field, the polysaccharides from algae can be used in controlled drug delivery, wound management, and regenerative medicine. This review will focus on the biomedical applications of marine polysaccharides from algae.
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