Integrating DNA strand-displacement circuitry with DNA tile self-assembly.
Integrating DNA strand-displacement circuitry with DNA tile self-assembly.
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DOI:
10.1038/ncomms2965
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发表时间:
2013
影响因子:
16.6
通讯作者:
中科院分区:
文献类型:
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DNA nanotechnology has emerged as a reliable and programmable way of controlling matter at the nanoscale through the specificity of Watson–Crick base pairing, allowing both complex self-assembled structures with nanometer precision and complex reaction networks implementing digital and analog behaviors. Here we show how two well-developed frameworks, DNA tile self-assembly and DNA strand-displacement circuits, can be systematically integrated to provide programmable kinetic control of self-assembly. We demonstrate the triggered and catalytic isothermal self-assembly of DNA nanotubes over 10 μm long from precursor DNA double-crossover tiles activated by an upstream DNA catalyst network. Integrating more sophisticated control circuits and tile systems could enable precise spatial and temporal organization of dynamic molecular structures. DNA tile self-assembly and DNA strand displacement circuits are well-developed frameworks in DNA nanotechnology. Here, the two approaches are combined to give programmable kinetic control of DNA nanotube self-assembly.
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影响因子:
14.9
作者:
Li B;Ellington AD;Chen X
通讯作者:
Chen X
影响因子:
56.9
作者:
Chworos, A;Severcan, I;Jaeger, L
通讯作者:
Jaeger, L
影响因子:
9.9
作者:
通讯作者:
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DOI:
10.1073/pnas.0407024101
发表时间:
2004-10-26
影响因子:
11.1
作者:
Dirks, RM;Pierce, NA
通讯作者:
Pierce, NA
影响因子:
64.8
作者:
通讯作者:
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