Effects of vaccine program against pandemic influenza A(H1N1) virus, United States, 2009-2010.

Effects of vaccine program against pandemic influenza A(H1N1) virus, United States, 2009-2010.
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DOI:
10.3201/eid1903.120394
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发表时间:
2013-03
影响因子:
11.8
通讯作者:
Meltzer MI
Meltzer MI
中科院分区:
医学2区
文献类型:
--
作者:
Borse RH;Shrestha SS;Fiore AE;Atkins CY;Singleton JA;Furlow C;Meltzer MI

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接种疫苗可能预防了70万至150万例临床病例,4000至10000例住院,200至500例死亡。2009年4月,美国开始应对大流行性流感病毒株A(H1N1)pdm 09的出现。2009年10月开始接种疫苗。通过使用美国监测数据(2009年4月12日至2010年4月10日)和疫苗覆盖率估计(2009年10月3日至2010年4月18日),我们估计A(H1N1)pdm09病毒疫苗接种计划预防了70万至150万例临床病例,4000至10000例住院病例和200至500例死亡病例。我们发现,接种疫苗的时间和疫苗的有效性对国民健康的影响很大。我们估计,对目标优先群体的优先接种建议并不劣于其他疫苗接种优先策略。这些结果强调需要相关的监测数据,以促进疫苗的建议和效果的快速评估。
Vaccination likely prevented 700,000–1,500,000 clinical cases, 4,000–10,000 hospitalizations, and 200–500 deaths. In April 2009, the United States began a response to the emergence of a pandemic influenza virus strain: A(H1N1)pdm09. Vaccination began in October 2009. By using US surveillance data (April 12, 2009–April 10, 2010) and vaccine coverage estimates (October 3, 2009–April 18, 2010), we estimated that the A(H1N1)pdm09 virus vaccination program prevented 700,000–1,500,000 clinical cases, 4,000–10,000 hospitalizations, and 200–500 deaths. We found that the national health effects were greatly influenced by the timing of vaccine administration and the effectiveness of the vaccine. We estimated that recommendations for priority vaccination of targeted priority groups were not inferior to other vaccination prioritization strategies. These results emphasize the need for relevant surveillance data to facilitate a rapid evaluation of vaccine recommendations and effects.
DOI: 10.1093/cid/ciq012
发表时间: 2011-01-01
影响因子: 11.8
作者:
Shrestha, Sundar S.;Swerdlow, David L.;Meltzer, Martin I.
通讯作者: Meltzer, Martin I.
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期刊: VACCINE
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