Satiety, but not total PYY, Is increased with continuous and intermittent exercise.

Satiety, but not total PYY, Is increased with continuous and intermittent exercise.
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DOI:
10.1002/oby.20335
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发表时间:
2013-10
期刊:
Obesity (Silver Spring, Md.)
影响因子:
--
通讯作者:
Kanaley JA
Kanaley JA
中科院分区:
其他
文献类型:
--
作者:
Holmstrup ME;Fairchild TJ;Keslacy S;Weinstock RS;Kanaley JA

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这项研究确定了肥胖个体对运动(1 小时连续运动与全天间歇运动)的荷尔蒙和主观食欲反应。 11 名肥胖受试者 (>30 kg/m2) 接受了 3 个 12 小时的研究日:控制条件(久坐行为 -SED)、连续运动条件((EX) 1 小时运动)和间歇运动条件((INT) 每小时 12 次、每次 5 分钟)。测量血样(每 10 分钟)的血清胰岛素和总肽 YY (PYY) 浓度,并评估食欲(视觉模拟量表-VAS:每 20 分钟)。计算曲线下总面积 (AUC)、2 小时 AUC 和基线以上 AUC,以及主观食欲评级。各条件之间的总 PYY AUC 没有观察到差异,但饥饿感随着 INT 的增加而降低(INT<EX;P<0.05),而饱腹感随着 SED 和 INT 条件的增加而增加(INT>EX 和 SED>EX;P<0.05)。总 PYY 和胰岛素水平(r=-0.81;P<0.05)以及总 PYY 和饱腹感(r=0.80;P<0.05)的变化与 EX 条件(而非 SED 和 INT 条件)之间存在相关性。在一天 12 小时的过程中,无论间歇性还是连续性运动,PYY 对膳食的总反应都不会改变;然而,对于肥胖者来说,间歇性运动比连续运动更能增加饱腹感并减少饥饿感。
This study determined the hormonal and subjective appetite responses to exercise (1-h continuous v. intermittent exercise throughout the day) in obese individuals. Eleven obese subjects (>30 kg/m2) underwent 3, 12-hour study days: control condition (sedentary behavior-SED), continuous exercise condition ((EX) 1-h exercise), and intermittent exercise condition ((INT) 12 hourly, 5-minute bouts). Blood samples (every 10 min) were measured for serum insulin and total peptide YY (PYY) concentrations, with ratings of appetite (visual analog scale-VAS: every 20 minutes). Both total area under the curve (AUC), 2-h AUC and AUC above baseline, and subjective appetite ratings were calculated. No differences were observed in total PYY AUC between conditions, but hunger was reduced with INT (INT<EX; P<0.05), and satiety was increased with both SED and INT conditions (INT>EX and SED>EX; P<0.05). A correlation existed between the change in total PYY and insulin levels (r=−0.81; P<0.05), and total PYY and satiety (r=0.80; P<0.05) with the EX condition, not the SED and INT conditions. The total PYY response to meals is not altered over the course of a 12-h day with either intermittent or continuous exercise; however, intermittent exercise increased satiety and reduced hunger to a greater extent than continuous exercise in obese individuals.
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