The subgingival periodontal microbiota of the aging mouth.
The subgingival periodontal microbiota of the aging mouth.
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DOI:
10.1111/prd.12136
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发表时间:
2016-10
影响因子:
18.6
通讯作者:
Faveri M
中科院分区:
文献类型:
--
作者:
Feres M;Teles F;Teles R;Figueiredo LC;Faveri M
Different mechanisms have been hypothesized to explain the increase in prevalence and severity of periodontitis in older adults, including shifts in the periodontal microbiota. However, the actual impact of aging in the composition of subgingival biofilms remains unclear. In the present article, we provide an overview of the composition of the subgingival biofilm in older adults and the potential effects of age on the oral microbiome. In particular, this review covers the following topics: (i) the oral microbiota of an aging mouth, (ii) the effects of age and time on the human oral microbiome, (iii) the potential impact of inflammaging and immunosenescence in the host-oral microbiota interactions, and (iv) the relationship of the aging oral microbiota and Alzheimer’s disease. Finally, in order to explore in greater breadth the potential effects of aging on the periodontal microbiota, we present analyses of data compiled from large clinical studies that evaluated the subgingival microbiota of periodontally healthy subjects and periodontitis patients from a wide age spectrum (20–83 years old). Those studies were conducted at Guarulhos University (São Paulo, SP, Brazil) and at The Forsyth Institute (Cambridge, USA), from 1999 to 2014.
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影响因子:
3.7
作者:
Biagi E;Nylund L;Candela M;Ostan R;Bucci L;Pini E;Nikkïla J;Monti D;Satokari R;Franceschi C;Brigidi P;De Vos W
通讯作者:
De Vos W
DOI:
10.1073/pnas.1002601107
发表时间:
2010-06-29
影响因子:
11.1
作者:
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通讯作者:
Knight, Rob
影响因子:
4.3
作者:
Eke PI;Dye BA;Wei L;Slade GD;Thornton-Evans GO;Borgnakke WS;Taylor GW;Page RC;Beck JD;Genco RJ
通讯作者:
Genco RJ
影响因子:
4.3
作者:
Faveri, Marcelo;Rebello, Allisson;Feres, Magda
通讯作者:
Feres, Magda
影响因子:
4
作者:
Capsoni, Simona;Carucci, Nicola Maria;Cattaneo, Antonino
通讯作者:
Cattaneo, Antonino