Forsythia suspensa Extract Has the Potential to Substitute Antibiotic in Broiler Chicken.
Forsythia suspensa Extract Has the Potential to Substitute Antibiotic in Broiler Chicken.
复制标题
连翘提取物具有替代肉鸡抗生素的潜力
DOI：
10.5713/ajas.2011.11425
复制
发表时间：
2012-04
期刊：
影响因子：
--
通讯作者：
Li P
中科院分区：
文献类型：
--
作者：
Han X;Piao XS;Zhang HY;Li PF;Yi JQ;Zhang Q;Li P
本研究通过两个试验探讨连翘提取物（FSE）替代抗生素在肉鸡中的应用潜力。首先，采用孔扩散法和2倍稀释法测定FSE对大肠杆菌K88、金黄色葡萄球菌和沙门氏菌的抑菌活性。观察到FSE对这些细菌生长的抑制作用。这种作用似乎是剂量依赖性的，在25.00、12.50、1.56 mg/ml后消失。第二，对252只肉仔鸡进行为期42天的试验，以评价日粮中添加FSE对肉仔鸡的影响。饲养程序包括从第1天至第21天的起始饲料和从第22天至第42天的育成饲料。饮食处理包括：i）NC：阴性对照组饲喂基于玉米-大豆粉的饮食; ii）PC：阳性对照组饲喂基于金霉素的饮食;以及iii）FC：试验组饲喂100 mg FSE/kg饮食。在这项研究中，生长性能没有不同的治疗在启动期间。与NC相比，日粮中添加金霉素和FSE显著提高了育成期和整个生长期的平均日增重（ADG）和平均日采食量（ADFI）（p<0.05）。日粮中钙的表观消化率、能量和钙的表观消化率均显著高于对照组（p<0.05）。此外，来自FC的鸡的盲肠大肠杆菌计数低于NC（p<0.05）。日粮中添加FSE还改善了（p<0.05）十二指肠和回肠中的绒毛高度和绒毛高度与隐窝深度的比率，并降低了（p<0.05）十二指肠中的隐窝深度。FC组的十二指肠绒毛高度和绒毛高度与十二指肠和回肠的隐窝深度比也较大（p<0.05）。不同处理对血清生长激素和IGF-1无明显影响。显然，FSE具有替代肉鸡抗生素的潜力。
Two experiments were conducted to investigate the potential for Forsythia suspensa extract (FSE) to substitute for antibiotic in broiler chicken. First, a well-diffusion assay procedure and a 2-fold dilution method were used to determine the bacteriostatic activity of FSE on Escherichia coli K88, staphylococcus aureus, and salmonella was assayed. An inhibitory effect of FSE was observed on the growth of these bacteria. This effect seems to be dose depended, which disappeared after 25.00, 12.50, 1.56 mg/ml. Second, a 42-d trial with 252 broiler chickens (d 1, 38.7±1.1 g BW) was conducted to evaluate the effect of dietary supplementation of FSE in broiler chicken. The feeding program consisted of a starter diet from d 1 to 21 and a finisher diet from d 22 to 42. Dietary treatments included were: i) NC: negative control fed a corn-soybean meal based diet; ii) PC: positive control group fed based diet with chlortetracycline; and iii) FC: a test group fed with 100 mg FSE/kg diet. In this study growth performance did not differ among treatments during the starter period. However, dietary supplemental chlortetracycline and FSE increased (p<0.05) average daily gain (ADG), average daily feed intake (ADFI) compared with NC during the finisher and overall phase. Apparent digestibility of calcium on d 21, digestibility of energy and calcium on d 42 of FC was greater (p<0.05) than NC. Moreover, cecal Escherichia coli counts for birds from FC were lower (p<0.05) than NC. Dietary FSE supplementation also improved (p<0.05) villus height and villus height to crypt depth ratios in both duodenum and ileum and decreased (p<0.05) crypt depth in the duodenum. Duodenum villus height and villus height to crypt depth ratio in both duodenum and ileum from the FC group were also greater (p<0.05). Serum growth hormone and IGF-1 were not influenced by different treatments. Apparently, FSE has the potential to substitute for antibiotic in broiler chicken.
登录
查看更多内容
影响因子：
2
作者：
NITSAN, Z;BENAVRAHAM, G;NIR, I
通讯作者：
NIR, I
DOI：
10.1007/s10295-007-0271-z
发表时间：
2008-02-01
影响因子：
3.4
作者：
Lima, Francisca Lucia;Roque de Carvalho, Maria Auxiliadora;Farias, Luiz de Macedo
通讯作者：
Farias, Luiz de Macedo
影响因子：
7.2
作者：
Piao, Xiang Lan;Cho, Eun Jung;Cui, Jian
通讯作者：
Cui, Jian
影响因子：
3.3
作者：
Qu, Huanhuan;Zhang, Yongmin;Sun, Wenji
通讯作者：
Sun, Wenji
影响因子：
1.8
作者：
Lien, T. F.;Homg, Y. M.;Wu, C. P.
通讯作者：
Wu, C. P.