The emotional face of anorexia nervosa: The neural correlates of emotional processing.
The emotional face of anorexia nervosa: The neural correlates of emotional processing.
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DOI：
10.1002/hbm.25417
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发表时间：
2021-07
影响因子：
4.8
通讯作者：
Tchanturia K
中科院分区：
文献类型：
--
作者：
Halls D;Leslie M;Leppanen J;Sedgewick F;Surguladze S;Fonville L;Lang K;Simic M;Nicholls D;Williams S;Tchanturia K
神经性厌食症（AN）的社会情绪处理困难已被报道，但其神经关联尚不清楚。以前的神经影像学工作是稀疏的，并没有使用功能连接范式来更充分地探索情绪困难的神经相关性。57名急性AN （AAN）不适女性、60名体重恢复AN （WR）女性和69名健康对照（HC）女性在接受功能磁共振成像时对一系列情绪面孔的性别进行了分类。AAN组平均年龄19.40岁（2.83岁），WR组平均年龄18.37岁（3.59岁），HC组平均年龄19.37岁（3.36岁）。采用全脑和心理物理相互作用连通性方法。从显著聚类中提取参数估计值并与临床症状相关联。虽然在全脑激活方面没有组水平差异，但在功能连接方面出现了显著的组水平差异。与AAN和HC相比，WR参与者在观看快乐的面孔时，显示出双侧枕部面部区域与扣带、中央前回、额上、中、内侧和下回之间的连通性增加。饮食失调症状与参数估计呈正相关。我们的发现在AN患者的大样本中描述了社交情绪处理的神经基础。神经性厌食症（AN）的社会情绪处理困难已被报道，但其神经关联尚不清楚。使用功能成像和功能连接方法，57名急性AN （AAN）不适女性、60名体重恢复AN （WR）女性和69名健康对照（HC）女性对一系列情绪面孔的性别进行了分类。当看到与饮食失调症状相关的快乐面孔时，与AAN和HC相比，WR参与者显示出双侧枕部面部区域与扣带、中央前回、额上回、中回、内侧和下回之间的连通性增加。
Social–emotional processing difficulties have been reported in Anorexia Nervosa (AN), yet the neural correlates remain unclear. Previous neuroimaging work is sparse and has not used functional connectivity paradigms to more fully explore the neural correlates of emotional difficulties. Fifty‐seven acutely unwell AN (AAN) women, 60 weight‐recovered AN (WR) women and 69 healthy control (HC) women categorised the gender of a series of emotional faces while undergoing Functional Magnetic Resonance Imaging. The mean age of the AAN group was 19.40 (2.83), WR 18.37 (3.59) and HC 19.37 (3.36). A whole brain and psychophysical interaction connectivity approach was used. Parameter estimates from significant clusters were extracted and correlated with clinical symptoms. Whilst no group level differences in whole brain activation were demonstrated, significant group level functional connectivity differences emerged. WR participants showed increased connectivity between the bilateral occipital face area and the cingulate, precentral gyri, superior, middle, medial and inferior frontal gyri compared to AAN and HC when viewing happy valenced faces. Eating disorder symptoms and parameter estimates were positively correlated. Our findings characterise the neural basis of social–emotional processing in a large sample of individuals with AN. Social–emotional processing difficulties have been reported in Anorexia Nervosa (AN), yet the neural correlates remain unclear. Using functional imaging and a functional connectivity approach, 57 acutely unwell AN (AAN) women, 60 weight‐recovered AN (WR) women and 69 healthy control (HC) women categorised the gender of a series of emotional faces. WR participants showed increased connectivity between the bilateral occipital face area and the cingulate, precentral gyri, superior, middle, medial and inferior frontal gyri compared to AAN and HC when viewing happy valenced faces which was correlated to eating disorder symptoms.
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影响因子：
4.8
作者：
Breukelaar IA;Antees C;Grieve SM;Foster SL;Gomes L;Williams LM;Korgaonkar MS
通讯作者：
Korgaonkar MS
在重度抑郁症的工作记忆更新过程中，视觉皮质激活和与前额叶皮层的连通性改变了。
DOI：
10.1016/j.nicl.2017.01.004
发表时间：
2017
期刊：
NeuroImage. Clinical
影响因子：
--
作者：
Le TM;Borghi JA;Kujawa AJ;Klein DN;Leung HC
通讯作者：
Leung HC
影响因子：
19.9
作者：
Etkin, Amit;Egner, Tobias;Kalisch, Raffael
通讯作者：
Kalisch, Raffael
影响因子：
56.9
作者：
Aviezer, Hillel;Trope, Yaacov;Todorov, Alexander
通讯作者：
Todorov, Alexander
影响因子：
2.9
作者：
Brewer, Judson A.;Garrison, Kathleen A.;Whitfield-Gabrieli, Susan
通讯作者：
Whitfield-Gabrieli, Susan