Nonstationary influence of El Niño on the synchronous dengue epidemics in Thailand.

Nonstationary influence of El Niño on the synchronous dengue epidemics in Thailand.
复制标题

DOI:
10.1371/journal.pmed.0020106
复制
发表时间:
2005-04
期刊:
影响因子:
15.8
通讯作者:
Hales S
Hales S
中科院分区:
医学1区
文献类型:
--
作者:
Cazelles B;Chavez M;McMichael AJ;Hales S

文献摘要

参考文献

被引文献

相似文献

包括环境和气候因素在内的几个因素影响媒介传播疾病的传播。然而,媒介传播疾病的气候因素的识别和相对重要性仍然存在争议。登革热是世界上最重要的病毒媒介传播疾病,关于气候影响的争议也适用于这种情况。在这里,我们讨论气候变异性在形成登革热疫情年际模式中的作用。我们使用小波方法分析了泰国从1983年到1997年的月度数据,这种方法可以描述非平稳现象,也可以量化时间序列之间的非平稳关联。我们报告了泰国每月的登革热发病率与2-3-y周期模式的厄尔尼诺动态之间的强烈关联。这种关联是不稳定的,仅在1986年至1992年出现,并似乎对泰国登革热疫情的同步性产生了重大影响。登革热疫情同步的潜在机制可能类似于起搏器,在起搏器中,内在的疾病动态与厄尔尼诺现象驱动的气候变化相互作用,以传播感染的传播波。当在2-3-y周期模式中与厄尔尼诺现象联系强烈时,人们观察到泰国各地登革热流行的高度同步性。当这种联系缺失时,季节动态就会占主导地位,在曼谷启动的同步就会崩溃。在泰国,登革热的传播模式很复杂,厄尔尼诺现象只与一些流行病有关;需要寻找其他原因才能引发其他疫情
Several factors, including environmental and climatic factors, influence the transmission of vector-borne diseases. Nevertheless, the identification and relative importance of climatic factors for vector-borne diseases remain controversial. Dengue is the world's most important viral vector-borne disease, and the controversy about climatic effects also applies in this case. Here we address the role of climate variability in shaping the interannual pattern of dengue epidemics. We have analysed monthly data for Thailand from 1983 to 1997 using wavelet approaches that can describe nonstationary phenomena and that also allow the quantification of nonstationary associations between time series. We report a strong association between monthly dengue incidence in Thailand and the dynamics of El Niño for the 2–3-y periodic mode. This association is nonstationary, seen only from 1986 to 1992, and appears to have a major influence on the synchrony of dengue epidemics in Thailand. The underlying mechanism for the synchronisation of dengue epidemics may resemble that of a pacemaker, in which intrinsic disease dynamics interact with climate variations driven by El Niño to propagate travelling waves of infection. When association with El Niño is strong in the 2–3-y periodic mode, one observes high synchrony of dengue epidemics over Thailand. When this association is absent, the seasonal dynamics become dominant and the synchrony initiated in Bangkok collapses. In Thailand, dengue transmission patterns are complex, with El Nino showing an association with some epidemics only; other reasons will need to be found for the initiation of other outbreaks
DOI: 10.1038/nature02225
发表时间: 2004-01-22
期刊: NATURE
影响因子: 64.8
作者:
Cummings, DAT;Irizarry, RA;Burke, DS
通讯作者: Burke, DS
DOI: 10.1098/rstb.2001.0894
发表时间: 2001-07-29
影响因子: 6.3
作者:
Kovats, RS;Campbell-Lendrum, DH;Cox, JS
通讯作者: Cox, JS
DOI: 10.1046/j.1365-2656.2003.00763.x
发表时间: 2003-11-01
影响因子: 4.8
作者:
Cazelles, B;Stone, L
通讯作者: Stone, L
DOI: 10.1086/420798
发表时间: 2004-06-01
影响因子: 2.9
作者:
Koelle, K;Pascual, M
通讯作者: Pascual, M
DOI: 10.2307/3434364
发表时间: 1999-02-01
影响因子: 10.4
作者:
Hales, S;Weinstein, P;Woodward, A
通讯作者: Woodward, A