The First Reported Case of Bordetella pertussis Bacteremia in a Patient With Human Immunodeficiency Virus Infection.
The First Reported Case of Bordetella pertussis Bacteremia in a Patient With Human Immunodeficiency Virus Infection.
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DOI：
10.1093/ofid/ofac020
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发表时间：
2022-03
影响因子：
4.2
通讯作者：
Oka S
中科院分区：
文献类型：
--
作者：
Wakimoto Y;Otsuka N;Yanagawa Y;Koide K;Kamachi K;Shibayama K;Teruya K;Kikuchi Y;Oka S
我们描述了一例人类免疫缺陷病毒感染患者的菌血症，由百日咳博德泰拉菌株缺乏2个主要毒力因子，丝状血凝素和菌毛引起。虽然百日咳B型菌血症并不常见，但医生应该意识到，即使是减毒百日咳B型菌株也可能导致免疫功能低下患者的侵袭性感染。百日咳博德泰拉是一种革兰氏阴性球菌，可引起严重的阵发性咳嗽疾病，即百日咳或百日咳。百日咳博德泰拉定植在人呼吸道的上皮细胞上，这种微生物通常是从鼻咽分离出来的。我们描述了一例百日咳杆菌血症患者与人类免疫缺陷病毒（HIV）感染。有趣的是，从血培养中回收的分离物没有产生主要的毒力因子，丝状血凝素（FHA）和菌毛（FIM）。此前，文献报道了3例百日咳杆菌血症。我们讨论百日咳杆菌血症的特点。
We describe a case of bacteremia in a human immunodeficiency virus–infected patient caused by a Bordetella pertussis strain lacking 2 major virulence factors, filamentous hemagglutinin and fimbriae. Although B pertussis bacteremia is uncommon, physicians should be aware that even attenuated B pertussis strains can cause invasive infection in immunocompromised patients. Bordetella pertussis is a gram-negative coccobacillus that causes a severe paroxysmal coughing disease known as whooping cough or pertussis. Bordetella pertussis colonizes the epithelial cells of the human respiratory tract, and the organisms are typically isolated from nasopharynx. We describe a case of B pertussis bacteremia in a patient with human immunodeficiency virus (HIV) infection. Interestingly, the isolate recovered from blood culture did not produce the major virulence factors, filamentous hemagglutinin (FHA) and fimbriae (FIM). Previously, 3 cases of B pertussis bacteremia were reported in the literature. We discuss the features of B pertussis bacteremia.
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影响因子：
11.8
作者：
Li, Lijun;Deng, Jikui;Yao, Kaihu
通讯作者：
Yao, Kaihu
影响因子：
11.8
作者：
Kamachi K;Duong HT;Dang AD;Hai T;Do D;Koide K;Otsuka N;Shibayama K;Hoang HTT
通讯作者：
Hoang HTT
影响因子：
3.1
作者：
BARENKAMP, SJ;LEININGER, E
通讯作者：
LEININGER, E
DOI：
10.1016/j.jinf.2005.04.014
发表时间：
2006-01-01
期刊：
The Journal of infection
影响因子：
--
作者：
Troseid, Marius;Jonassen, Tom Oystein;Steinbakk, Martin
通讯作者：
Steinbakk, Martin
影响因子：
3.7
作者：
Moriuchi T;Otsuka N;Hiramatsu Y;Shibayama K;Kamachi K
通讯作者：
Kamachi K