Amygdala lesions selectively impair familiarity in recognition memory.
Amygdala lesions selectively impair familiarity in recognition memory.
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DOI:
10.1038/nn.2919
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发表时间:
2011-09-25
影响因子:
25
通讯作者:
Eichenbaum H
中科院分区:
文献类型:
--
作者:
Farovik A;Place RJ;Miller DR;Eichenbaum H
A major controversy in the study of memory concerns whether there are distinct medial temporal lobe (MTL) substrates of recollection and familiarity. Studies using Received Operating Characteristics (ROC) analyses of recognition memory indicate that the hippocampus is essential to recollection but not familiarity. We report the converse pattern wherein amygdala damage impairs familiarity while sparing recollection. Combined with previous findings, these results dissociate recollection and familiarity by selective MTL damage.
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DOI:
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