A single microcircuit with multiple functions: state dependent information processing in the hippocampus.

A single microcircuit with multiple functions: state dependent information processing in the hippocampus.
复制标题

DOI:
10.1016/j.conb.2012.03.007
复制
发表时间:
2012-08
影响因子:
5.7
通讯作者:
Frank LM
Frank LM
中科院分区:
医学2区
文献类型:
--
作者:
Carr MF;Frank LM

文献摘要

参考文献

被引文献

相似文献

许多神经电路以多种不同的模式处理信息。例如,海马体参与记忆编码、检索和巩固过程。这些不同的助记计算需要处理当前感觉输入和先前存储的关联的不同平衡。在这里,我们探索了与不同信息处理状态相关的海马区CA1区的活动模式。我们讨论了将这些模式与CA1的特定输入联系起来的证据,并描述了与突触驱动平衡有关的行为因素。我们认为,了解影响海马体回路信息流的因素可以为如何动态重新配置神经回路以在不同时间执行不同功能提供重要的新见解。
Many neural circuits process information in multiple distinct modes. For example, the hippocampus is involved in memory encoding, retrieval, and consolidation processes. These different mnemonic computations require processing of differing balances of current sensory input and previously stored associations. Here we explore patterns of activity in hippocampal output area CA1 associated with different information processing states. We discuss the evidence linking these patterns to specific inputs to CA1 and describe behavioral factors that are related to the balance of synaptic drive. We suggest that understanding the factors that influence information flow in the hippocampal circuit could provide important new insights into how neural circuits are reconfigured on the fly to perform different functions at different times.
DOI: 10.1038/nn.2599
发表时间: 2010-08
影响因子: 25
作者:
Dupret, David;O'Neill, Joseph;Pleydell-Bouverie, Barty;Csicsvari, Jozsef
通讯作者: Csicsvari, Jozsef
DOI: 10.1016/j.neuron.2010.04.013
发表时间: 2010-05-27
期刊: Neuron
影响因子: 16.2
作者:
Chevaleyre V;Siegelbaum SA
通讯作者: Siegelbaum SA
DOI: 10.1126/science.1204622
发表时间: 2011-07-15
期刊: Science (New York, N.Y.)
影响因子: --
作者:
Luo AH;Tahsili-Fahadan P;Wise RA;Lupica CR;Aston-Jones G
通讯作者: Aston-Jones G
DOI: 10.1126/science.1099901
发表时间: 2004-08-27
期刊: SCIENCE
影响因子: 56.9
作者:
Fyhn, M;Molden, S;Moser, MB
通讯作者: Moser, MB
DOI: 10.1038/nn.2384
发表时间: 2009-10-01
影响因子: 25
作者:
Girardeau, Gabrielle;Benchenane, Karim;Zugaro, Michael B.
通讯作者: Zugaro, Michael B.