Effect of cataract surgery on cognitive function in elderly: Results of Fujiwara-kyo Eye Study.
Effect of cataract surgery on cognitive function in elderly: Results of Fujiwara-kyo Eye Study.
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DOI：
10.1371/journal.pone.0192677
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发表时间：
2018
期刊：
影响因子：
3.7
通讯作者：
Ogata N
中科院分区：
文献类型：
--
作者：
Miyata K;Yoshikawa T;Morikawa M;Mine M;Okamoto N;Kurumatani N;Ogata N
旨在确定日本老年人队列中既往白内障手术与认知功能之间是否存在显着关联。奈良医科大学，奈良，日本。藤原京眼科研究是一项横断面流行病学研究。受试者年龄≥ 68 岁，居住在奈良县，并对招募通知做出反应。所有受试者均接受了全面的眼科检查，并回答了有关其社会人口统计和病史（包括既往白内障手术史）的调查问卷。确定了既往白内障手术与认知功能之间的关联。总共研究了 2764 名受试者，平均年龄为 76.3±4.8 岁（±标准差）。其中，668 人（24.2%）接受过白内障手术。其中，150 人（5.4%）经简易精神状态检查（MMSE）评分≤23 确定患有痴呆，877 人（31.7%）患有轻度认知障碍（MCI；MMSE 评分 24-26）。调整年龄、性别、体重指数、教育程度、高血压、糖尿病、抑郁症和中风病史后，既往接受过白内障手术的受试者发生 MCI 的比值比 (OR) 显着低于未接受过白内障手术的受试者（OR = 0.78，95% 置信区间；CI 0.64-0.96，P = 0.019）。当视力也添加到调整因素中时，OR 仍然较低（OR 0.79，95% CI 0.64–0.97，P = 0.025）。然而，先前的白内障手术对痴呆症的低 OR 没有显着影响。白内障手术可能在降低发展为 MCI 的风险方面发挥作用，与视力无关，但对痴呆症没有作用。
To determine whether there is a significant association between prior cataract surgery and cognitive function in an elderly Japanese cohort. Nara Medical University, Nara, Japan. The Fujiwara-kyo Eye Study was a cross-sectional epidemiological study. The subjects were ≥ 68-years who lived in the Nara Prefecture and responded to recruitment notices. All of the subjects received comprehensive ophthalmological examinations, and answered questionnaires on their socio-demographic and medical history including prior cataract surgery. The association between prior cataract surgery and cognitive function was determined. A total of the 2764 subjects whose mean age was 76.3±4.8 years (±standard deviation) was studied. Of these, 668 individuals (24.2%) had undergone cataract surgery. Of these, 150 (5.4%) had dementia as determined by the Mini-Mental State Examination (MMSE) score ≤23, and 877 individuals (31.7%) had mild cognitive impairment (MCI; MMSE score 24–26). The subjects who had prior cataract surgery had significantly lower odds ratio (OR) of having MCI (OR = 0.78, 95% confidence interval; CI 0.64–0.96, P = 0.019) than those who had not had cataract surgery after adjusting for age, sex, body mass index, education, hypertension, diabetes, depression, and history of stroke. The OR was still lower when the visual acuity was also added to the adjusted factors (OR 0.79, 95% CI 0.64–0.97, P = 0.025). However, prior cataract surgery did not contribute significantly to the low OR for dementia. Cataract surgery may play a role in reducing the risk of developing MCI independently of visual acuity but not for dementia.
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影响因子：
4.7
作者：
Nezu S;Okamoto N;Morikawa M;Saeki K;Obayashi K;Tomioka K;Komatsu M;Iwamoto J;Kurumatani N
通讯作者：
Kurumatani N
影响因子：
7.2
作者：
Gussekloo, J;de Craen, AJM;Westendorp, RGJ
通讯作者：
Westendorp, RGJ
DOI：
10.1017/s1355617706060954
发表时间：
2006-09-01
影响因子：
2.6
作者：
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通讯作者：
Von Sanden, Chwee
影响因子：
9.9
作者：
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通讯作者：
Monsell, Sarah E.
影响因子：
5.4
作者：
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通讯作者：
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