The allergenicity of complex cations.
The allergenicity of complex cations.
复制标题
复杂阳离子的致敏性。
DOI:
10.1016/0006-291x(86)90966-6
复制
发表时间:
1986
影响因子:
3.1
通讯作者:
Wood,JM
中科院分区:
文献类型:
--
作者:
Schallreuter,KU;Wood,JM
A homologous series of eight quaternary ammonium salts (quats) were used as complex cations in a survey of contact hypersensitivity in guinea pigs. Two of the quats tested were found to be strong allergens which was due to stable association with membrane lipids at the surface of epidermal cells. This surface complexation reaction was studied in detail by using a spin-labelled quat of intermediate allergenicity. Electron spin resonance was used to show that stable “ion pairs” are formed between membrane receptor sites and the two strong allergens. Information was obtained on the specificity and kinetics of immunogenic complex formation as well as on the position and orientation of these haptens on epidermal receptor sites in vivo.
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DOI:
10.1136/bmj.284.6313.417-a
发表时间:
1982
期刊:
British Medical Journal (Clinical research ed.)
影响因子:
--
作者:
R. Schoeffel;S. Anderson;R. Altounyan
通讯作者:
R. Altounyan
影响因子:
4.1
作者:
R. Dawber;C. Calnan
通讯作者:
C. Calnan
影响因子:
2.9
作者:
J. Hsia;J. R. Little
通讯作者:
J. R. Little
DOI:
10.1136/bmj.283.6302.1297-a
发表时间:
1981
期刊:
British Medical Journal (Clinical research ed.)
影响因子:
--
作者:
H. Åberg;C. Mörlin;G. Frithz
通讯作者:
G. Frithz
影响因子:
--
作者:
A. Fisher;M. A. Stillman
通讯作者:
M. A. Stillman