Mucosal vaccines for SARS-CoV-2: scientific gaps and opportunities-workshop report.

Mucosal vaccines for SARS-CoV-2: scientific gaps and opportunities-workshop report.
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DOI:
10.1038/s41541-023-00654-6
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发表时间:
2023-04-12
期刊:
影响因子:
9.2
通讯作者:
--
中科院分区:
医学1区
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--
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2022 年 11 月 7 日至 8 日,美国国立卫生研究院 (NIH) 下属的国家过敏和传染病研究所 (NIAID)、流行病防范创新联盟 (CEPI)、比尔及梅琳达·盖茨基金会 (BMGF)、生物医学高级研究与发展局 (BARDA) 和 Wellcome Trust 主办了一场题为“粘膜疫苗SARS-CoV-2:科学差距和机遇。”研讨会期间,来自世界各地的研究人员和疫苗研发人员讨论了粘膜疫苗阻断 SARS-CoV-2 传播的潜力,并回顾了 SARS-CoV-2 粘膜疫苗的研究现状。在此,我们总结了会议期间强调的基础、转化和临床研究方面的主要挑战和机遇。我们还提供了推动该领域发展并加速 SARS-CoV-2 粘膜疫苗开发的建议。
On November 7th and 8th, 2022, The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), The Coalition for Epidemic Preparedness Innovation (CEPI), The Bill & Melinda Gates Foundation (BMGF), The Biomedical Advanced Research and Development Authority (BARDA), and the Wellcome Trust hosted a virtual workshop entitled “Mucosal Vaccines for SARS-CoV-2: Scientific Gaps and Opportunities.” During the workshop, researchers and vaccine developers from around the world discussed the potential of mucosal vaccines to block SARS-CoV-2 transmission and reviewed the status of SARS-CoV-2 mucosal vaccine research. Here, we summarize key challenges and opportunities in basic, translational, and clinical research that were highlighted during the meeting. We also provide recommendations to advance the field and accelerate the development of mucosal vaccines for SARS-CoV-2.
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