Adult Health and Early Life Adversity: Behind the Curtains of Maternal Care Research.
Adult Health and Early Life Adversity: Behind the Curtains of Maternal Care Research.
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DOI：
10.3389/fphys.2022.804239
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发表时间：
2022
影响因子：
4
通讯作者：
Dumas TC
中科院分区：
文献类型：
--
作者：
Dumas TC
一个人成年后的健康质量和在衰老过程中保持认知能力的机会直接取决于他在婴儿时期所得到的护理质量。对产妇护理的正式研究至少可以追溯到一个世纪。在灵长类动物中，母亲剥夺后的行为结果的揭示，随后发现了啮齿类动物中由子代-后代关系介导的全身和大脑生长因子。最近，产妇护理的遗传/表观遗传基础已被确定，并与成人健康和衰老的认知能力呈正相关。这个领域的历史既悲惨又迷人。早期的灵长类动物研究虽然提供了大量信息，但却充满了辱骂。最初的啮齿动物研究在其重要性得到承认之前受到了嘲笑。最后一个教训是，婴儿/幼儿护理很重要。今天，我们更好地了解了产妇护理的生物学基础及其代际传播，以及按摩早产儿和拥抱我们的孩子的科学依据。
The quality of one’s adult health and the chances of maintaining cognitive ability in aging stem directly from the quality of care one receives as an infant. Formal studies of maternal care can be traced back at least a century. Revelations of behavioral outcomes after maternal deprivation in primates were followed by discoveries of systemic and brain growth factors mediated by the caregiver–offspring relationship in rodents. More recently, much of the genetic/epigenetic bases of maternal care has been defined and positively linked to adult health and cognitive ability in senescence. The history of this field is both tragic and fascinating. The early primate work, while informative, was abusive. The initial rodent work was ridiculed before its importance was recognized. The final lesson learned is that infant/toddler care matters a lot. Today, we have a better understanding of the biology underlying maternal care and its transmission across generations as well as a scientific basis for massaging premature infants and hugging our children.
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影响因子：
6.4
作者：
Fisher PA;Frenkel TI;Noll LK;Berry M;Yockelson M
通讯作者：
Yockelson M
影响因子：
3.3
作者：
Hofer, MA
通讯作者：
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DOI：
10.1097/nmc.0000000000000177
发表时间：
2015-11-01
影响因子：
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作者：
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通讯作者：
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影响因子：
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作者：
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通讯作者：
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影响因子：
16.4
作者：
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通讯作者：
HARLOW, HF