Lysogenic Streptococcus suis isolate SS2-4 containing prophage SMP showed increased mortality in zebra fish compared to the wild-type isolate.
Lysogenic Streptococcus suis isolate SS2-4 containing prophage SMP showed increased mortality in zebra fish compared to the wild-type isolate.
复制标题
DOI:
10.1371/journal.pone.0054227
复制
发表时间:
2013
期刊:
影响因子:
3.7
通讯作者:
Lu C
中科院分区:
文献类型:
--
作者:
Tang F;Zhang W;Lu C
Streptococcus suis (S. suis) infection is considered to be a major problem in the swine industry worldwide. Based on the capsular type, 33 serotypes of S. suis have been described, with serotype 2 (SS2) being the most frequently isolated from diseased piglets. Little is known, however, about the pathogenesis and virulence factors of S. suis. Research on bacteriophages highlights a new area in S. suis research. A S. suis serotype 2 bacteriophage, designated SMP, has been previously isolated in our laboratory. Here, we selected a lysogenic isolate in which the SMP phage was integrated into the chromosome of strain SS2-4. Compared to the wild-type isolate, the lysogenic strain showed increased mortality in zebra fish. Moreover the sensitivity of the lysogenic strain to lysozyme was seven times higher than that of the wild-type.
登录
查看更多内容
影响因子:
5.4
作者:
LIN, L;BITNER, R;EDLIN, G
通讯作者:
EDLIN, G
影响因子:
3.2
作者:
Ju, Cun-Xiang;Gu, Hong-Wei;Lu, Cheng-Ping
通讯作者:
Lu, Cheng-Ping
影响因子:
3.3
作者:
Ma, Y. L.;Lu, C. P.
通讯作者:
Lu, C. P.
DOI:
10.1016/s0732-8893(02)00474-1
发表时间:
2002-12-01
影响因子:
2.9
作者:
Beutin, L;Kaulfuss, S;Smith, HR
通讯作者:
Smith, HR
影响因子:
3.6
作者:
Bae, Taeok;Baba, Tadashi;Schneewind, Olaf
通讯作者:
Schneewind, Olaf