Effects of Air Pollution on Asthma Hospitalization Rates in Different Age Groups in Metropolitan Cities of Korea.

Effects of Air Pollution on Asthma Hospitalization Rates in Different Age Groups in Metropolitan Cities of Korea.
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DOI:
10.1007/s11869-013-0195-x
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发表时间:
2013-09-01
影响因子:
5.1
通讯作者:
Yun-Chul, Hong
Yun-Chul, Hong
中科院分区:
环境科学与生态学4区
文献类型:
--
作者:
Park, Minjeong;Luo, Sheng;Kwon, Jaymin;Stock, Thomas H.;Delclos, George;Kim, Ho;Yun-Chul, Hong

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许多研究表明空气污染与韩国哮喘入院率之间存在关联,但尚未报道这些影响是否因年龄分类而异。本研究的目的是确定空气污染对哮喘住院的影响是否因三个年龄组(岁)而不同:儿童(小于15岁),成人(15-64岁;参考组)和老年人(65岁以上)。分两个阶段分析了韩国七个大城市的日常时间序列数据。在第一阶段,使用半参数对数线性回归,估计每个城市和年龄组与空气污染相关的相对哮喘发病率。在第二阶段,使用贝叶斯分层模型按年龄组合并了所有七个城市的估计数。暴露于空气动力学直径<10微米的颗粒物(PM10)、一氧化碳(CO)和二氧化氮(NO2)的影响因年龄组而异。以成年人为参照,PM10升高10μg/m3时哮喘入院的相对率(RR)为1.5(95%CI:0.1-2.8%)儿童较低,1.3%(95% CI:0.7-1.9%)老年人更高; CO增加1 ppm的RR为1.9%(95% CI:0.3-3.8%);老年人NO2增加1 ppb(1 ppb)的RR高0.5%(95% CI:0.3-0.7%)。臭氧或二氧化硫的相对比率没有显着的年龄组差异。
Many studies have shown associations between air pollution and asthma admissions in Korea, but have not reported whether these effects differ by age classification. The purpose of this study was to determine whether air pollution effects on asthmatic hospital admissions are different by three age groups (years): children (less than 15), adults (15–64; reference group), and the elderly (over 65). Daily time-series data from seven metropolitan cities in South Korea were analyzed in two stages. In the first stage, relative asthma morbidity rates associated with air pollution were estimated for each city and age group, using semi-parametric log-linear regression. In the second stage, estimates from all seven cities were combined by age group using Bayesian hierarchical modeling. The effects of exposure to particulate matter <10 micrometers in aerodynamic diameter (PM10), carbon monoxide (CO) and nitrogen dioxide (NO2) varied significantly by age groups. Using adults as the referent, the relative rate (RR) of asthma admissions with 10μg/m3 increase of PM10 is 1.5% (95%CI: 0.1–2.8%) lower for children, and 1.3% (95% CI: 0.7–1.9%) higher for the elderly; RR with 1ppm increase of CO is 1.9% (95% CI: 0.3–3.8%) lower for children; RR with 1ppb increase of NO2(1ppb) is 0.5% (95% CI: 0.3–0.7%) higher for the elderly. No significant age group difference in relative rate was found for ozone or sulfur dioxide.
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