No evidence for environmental transmission risk of SARS-CoV-2 in the UK's largest urban river system: London as a case study
No evidence for environmental transmission risk of SARS-CoV-2 in the UK's largest urban river system: London as a case study
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没有证据表明英国最大的城市河流系统存在 SARS-CoV-2 的环境传播风险：以伦敦为例
DOI：
10.1101/2022.03.16.22272465
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发表时间：
2022
期刊：
影响因子：
--
通讯作者：
Ransome E
中科院分区：
文献类型：
--
作者：
Ransome E
许多国家已证实未经处理的污水中存在SARS-CoV-2，但对受污染淡水中的发病率和感染风险仍知之甚少。英国的泰晤士河接收来自57个联合下水道溢流（CSO）的未经处理的污水，其中许多每年排放数十次。我们调查了这种排放是否为SARS-CoV-2的环境传播提供了途径。在泰晤士河上收集了接近六个民间社会组织的废水，地表水和沉积物样本，进行了为期8个月的SARS-CoV-2 RNA和传染性病毒检测。对双壳贝类进行取样，作为病毒生物累积的哨兵种属。来自塞尔维亚多瑙河和萨瓦河的沉积物和水样作为阳性对照进行了分析，这些河流也大量排放未经处理的污水。我们在英国样本中没有发现SARS-CoV-2 RNA或传染性病毒的证据，而在塞尔维亚的水和沉积物样本中却发现了RNA阳性。此外，我们发现感染性SARS-CoV-2接种物在泰晤士河水和沉积物中稳定< 3天，而RNA至少在7天内保持可检测性。这表明废水的稀释可能会限制环境传播，感染性应纳入未来病原体溢出的风险评估。
The presence of SARS-CoV-2 in untreated sewage has been confirmed in many countries but its incidence and infection risk in contaminated freshwaters is still poorly understood. The River Thames in the UK receives untreated sewage from 57 Combined Sewer Overflows (CSOs), with many discharging dozens of times per year. We investigated if such discharges provide a pathway for environmental transmission of SARS-CoV-2. Samples of wastewater, surface water, and sediment collected close to six CSOs on the River Thames were assayed over 8 months for SARS-CoV-2 RNA and infectious virus. Bivalves were sampled as sentinel species of viral bioaccumulation. Sediment and water samples from the Danube and Sava rivers in Serbia, where raw sewage is also discharged in high volumes, were assayed as a positive control. We found no evidence of SARS-CoV-2 RNA or infectious virus in UK samples, in contrast to RNA positive water and sediment samples from Serbia. Furthermore, we show that infectious SARS-CoV-2 inoculum is stable in Thames water and sediment for < 3 days, while RNA remained detectable for at least seven days. This indicates that dilution of wastewater likely limits environmental transmission, and that infectivity should be embedded in future risk assessments of pathogen spillover.
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塞尔维亚多瑙河中的SARS-COV-2 RNA检测与未经处理的废水的排放有关。
影响因子：
9.8
作者：
Kolarevic, Stoimir;Micsinai, Adrienn;Szanto-Egesz, Reka;Lukacs, Alena;Kracun-Kolarevic, Margareta;Lundy, Lian;Kirschner, Alexander K. T.;Farnleitner, Andreas H.;Djukic, Aleksandar;Colic, Jasna;Nenin, Tanja;Sunjog, Karolina;Paunovic, Momir
通讯作者：
Paunovic, Momir
新西兰基流条件下河流中大肠杆菌浓度的变化。
影响因子：
2.4
作者：
R. Muirhead;E. Meenken
通讯作者：
E. Meenken
影响因子：
10.9
作者：
Kongprajug, Akechai;Mongkolsuk, Skorn;Sirikanchana, Kwanrawee
通讯作者：
Sirikanchana, Kwanrawee
DOI：
10.1016/j.scitotenv.2018.12.108
发表时间：
2019-03
期刊：
The Science of the total environment
影响因子：
--
作者：
Kelly Munro;C. Martins;M. Loewenthal;S. Comber;D. Cowan;Luisa Pereira;L. Barron
通讯作者：
Kelly Munro;C. Martins;M. Loewenthal;S. Comber;D. Cowan;Luisa Pereira;L. Barron
DOI：
10.1016/j.scitotenv.2021.146270
发表时间：
2021-07-15
期刊：
The Science of the total environment
影响因子：
--
作者：
Desdouits M;Piquet JC;Wacrenier C;Le Mennec C;Parnaudeau S;Jousse S;Rocq S;Bigault L;Contrant M;Garry P;Chavanon F;Gabellec R;Lamort L;Lebrun L;Le Gall P;Meteigner C;Schmitt A;Seugnet JL;Serais O;Peltier C;Bressolette-Bodin C;Blanchard Y;Le Guyader FS
通讯作者：
Le Guyader FS