Real-time associations between young adults' momentary pain and prescription opioid misuse intentions in daily life.
Real-time associations between young adults' momentary pain and prescription opioid misuse intentions in daily life.
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DOI：
10.1037/amp0000648
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发表时间：
2020-09
期刊：
影响因子：
--
通讯作者：
Curtin JJ
中科院分区：
文献类型：
--
作者：
Papp LM;Kouros CD;Curtin JJ
控制疼痛已被确定（主要通过回顾性报告）是个人滥用处方阿片类药物的强大动力。然而，令人惊讶的是，很少有工作直接检验短暂的疼痛经历是否与日常生活中处方阿片类药物滥用有关。参与者包括 297 名因近期滥用处方药而招募的年轻大学生。利用 28 天的生态瞬时评估来收集参与者的疼痛经历以及处方阿片类药物滥用意图和行为。分层广义线性模型和二元逻辑回归检验了假设。研究结果显示，考虑到报告时间、参与者性别和背景物质使用情况，较高的即时疼痛与滥用处方阿片类药物的意图呈正相关。此外，人与人之间的结果表明，在报告期内报告疼痛程度较高的参与者更有可能打算在日常生活中滥用处方阿片类药物。尽管实际误用频率较低，但报告期内较高的疼痛评级与误用行为的可能性较大之间也存在类似的可靠关联。观察到可靠的调节：正如假设的那样，与男性相比，女性的短暂疼痛和误用意图之间的内部关联更强。此外，对于那些报告有问题的饮酒水平较低（相对较高）的人来说，疼痛和滥用意图之间的内部联系更强。这与假设的方向不一致。了解大学生的痛苦在他们滥用处方阿片类药物的意图中所扮演的角色对于为未来的研究和预防工作提供信息非常重要。
Managing pain has been identified (mainly through retrospective reports) as a robust motivator for individuals engaging in prescription opioid misuse. However, surprisingly little work has directly examined whether momentary pain experiences are associated with prescription opioid misuse in daily life. Participants included 297 young-adult college students recruited on the basis of recent prescription drug misuse. Ecological momentary assessment over a 28-day period was utilized to collect participants’ pain experiences and prescription opioid misuse intention and behavior. Hierarchical generalized linear modeling and binary logistic regression tested hypotheses. Findings revealed that higher in-the-moment pain was positively associated with intentions to engage in prescription opioid misuse, accounting for report timing and participant sex and background substance use. Also, the between-person result indicated that participants who reported higher levels of pain across the reporting period were more likely to intend to misuse prescription opioids in daily life. There was a similar reliable association between higher pain ratings across the reporting period and greater likelihood of engaging in misuse behavior, although actual misuse frequency was low. Reliable moderation was observed: As hypothesized, the within-person association between momentary pain and misuse intentions was stronger for females compared to males. Also, the within-person link between pain and misuse intentions was stronger for those who reported lower (vs. higher) levels of problematic alcohol use; this was not consistent with the hypothesized direction. Understanding the role of college students’ pain in their intentions to engage in prescription opioid misuse is important for informing future research and prevention efforts.
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影响因子：
3.4
作者：
Cooney, Ned L.;Litt, Mark D.;Oncken, Cheryl A.
通讯作者：
Oncken, Cheryl A.
影响因子：
3.7
作者：
Harries, Michael D.;Lust, Katherine;Grant, Jon E.
通讯作者：
Grant, Jon E.
影响因子：
4.4
作者：
Cleveland, H. Harrington;Harris, Kitty S.
通讯作者：
Harris, Kitty S.
影响因子：
8
作者：
Boyd, Carol J.;McCabe, Sean Esteban;Young, Amy
通讯作者：
Young, Amy
DOI：
10.1126/science.aau1184
发表时间：
2018-09-21
期刊：
Science (New York, N.Y.)
影响因子：
--
作者：
Jalal H;Buchanich JM;Roberts MS;Balmert LC;Zhang K;Burke DS
通讯作者：
Burke DS