Domain-specific expression of meristematic genes is defined by the LITTLE ZIPPER protein DTM in tomato
Domain-specific expression of meristematic genes is defined by the LITTLE ZIPPER protein DTM in tomato
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番茄中 LITTLE ZIPPER 蛋白 DTM 定义了分生组织基因的域特异性表达
DOI:
10.1038/s42003-019-0368-8
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发表时间:
2019-04
影响因子:
5.9
通讯作者:
Xiao Han
中科院分区:
文献类型:
--
作者:
Xu Qian;Li Rong;Weng Lin;Sun Yuan;Li Meng;Xiao Han
Shoot meristems, which harbor a small population of stem cells, are responsible for generating new above-ground organs in plants. The proliferation and differentiation of these stem cells is regulated by a genetic pathway involving two key meristematic genes:CLAVATA3(CLV3) andWUSCHEL(WUS). However, it is not well understood howCLV3andWUSexpression domains in the shoot meristems are specified and maintained during post-embryogenic development. Here, we show that a tomato mutant with fasciated stems, flowers and fruits, due to impaired stem cell activity, is defective in a LITTLE ZIPPER gene denoted asDEFECTIVE TOMATO MERISTEM(DTM). DTM forms a negative feedback loop with class III homeodomain-leucine zipper (HD-ZIP III) transcription factors to confineCLV3andWUSexpression to specific domains of the shoot meristems. Our findings reveal a new layer of complexity in the regulation of plant stem cell homeostasis.
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影响因子:
4.5
作者:
Shi B;Zhang C;Tian C;Wang J;Wang Q;Xu T;Xu Y;Ohno C;Sablowski R;Heisler MG;Theres K;Wang Y;Jiao Y
通讯作者:
Jiao Y
影响因子:
56.9
作者:
Fletcher, LC;Brand, U;Meyerowitz, EM
通讯作者:
Meyerowitz, EM
影响因子:
4.6
作者:
S. Clark;S. Jacobsen;J. Levin;E. Meyerowitz
通讯作者:
S. Clark;S. Jacobsen;J. Levin;E. Meyerowitz
影响因子:
7.4
作者:
Lin Weng;Fangfang Zhao;Rong Li;Changjie Xu;Kun-song Chen;Han Xiao
通讯作者:
Lin Weng;Fangfang Zhao;Rong Li;Changjie Xu;Kun-song Chen;Han Xiao
影响因子:
6.2
作者:
MCCORMICK, S;NIEDERMEYER, J;FRALEY, R
通讯作者:
FRALEY, R