The effects of components of fine particulate air pollution on mortality in california: results from CALFINE.
The effects of components of fine particulate air pollution on mortality in california: results from CALFINE.
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细颗粒空气污染的成分对加利福尼亚州死亡率的影响：钙钙的结果。
DOI：
10.1289/ehp.9281
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发表时间：
2007-01
影响因子：
10.4
通讯作者：
Lipsett, Michael
中科院分区：
文献类型：
--
作者：
Ostro, Bart;Feng, Wen-Ying;Broadwin, Rachel;Green, Shelley;Lipsett, Michael
一些流行病学研究提供了每日死亡率与直径为2.5μm的颗粒物(PM2.5)之间存在关联的证据。然而，人们对PM2.5成分的相对影响知之甚少。我们研究了加州六个县的19种PM2.5成分与每日死亡率之间的关系。我们获得了2000年至2003年死亡率和PM2.5质量和成分的每日数据，包括元素碳和有机碳(EC和OC)、硝酸盐、硫酸盐和各种金属。我们检查了PM2.5及其成分与几个死亡类别的每日计数的关系：全因、心血管、呼吸系统和65岁的死亡率。使用包含自然样条线的泊松回归来控制时变协变量。为每个县的每个组成部分确定了影响估计，然后使用随机影响模型进行组合。PM2.5质量和几种成分与多种死亡类别有关，特别是心血管死亡。例如，对于3天的滞后，后者分别增加了1.6%、2.1%、1.6%和1.5%的PM2.5、EC、OC和硝酸盐，四分位数范围分别为14.6%、0.8%、4.6%和5.5%μg/m~3。在凉爽的季节，死亡率与包括硫酸盐和几种金属在内的额外污染物之间的相关性更强。这一多项分析增加了越来越多的证据将PM2.5与死亡率联系起来，并表明额外的风险可能因PM2.5的具体组成部分而异。因此，使用基于PM2.5质量的回归系数可能低估了与某些PM2.5组分的关联。此外，我们的发现支持了与燃烧相关的污染物在加利福尼亚州特别重要的假设。
Several epidemiologic studies provide evidence of an association between daily mortality and particulate matter < 2.5 μm in diameter (PM2.5). Little is known, however, about the relative effects of PM2.5 constituents. We examined associations between 19 PM2.5 components and daily mortality in six California counties. We obtained daily data from 2000 to 2003 on mortality and PM2.5 mass and components, including elemental and organic carbon (EC and OC), nitrates, sulfates, and various metals. We examined associations of PM2.5 and its constituents with daily counts of several mortality categories: all-cause, cardiovascular, respiratory, and mortality age > 65 years. Poisson regressions incorporating natural splines were used to control for time-varying covariates. Effect estimates were determined for each component in each county and then combined using a random-effects model. PM2.5 mass and several constituents were associated with multiple mortality categories, especially cardiovascular deaths. For example, for a 3-day lag, the latter increased by 1.6, 2.1, 1.6, and 1.5% for PM2.5, EC, OC, and nitrates based on interquartile ranges of 14.6, 0.8, 4.6, and 5.5 μg/m3, respectively. Stronger associations were observed between mortality and additional pollutants, including sulfates and several metals, during the cool season. This multicounty analysis adds to the growing body of evidence linking PM2.5 with mortality and indicates that excess risks may vary among specific PM2.5 components. Therefore, the use of regression coefficients based on PM2.5 mass may underestimate associations with some PM2.5 components. Also, our findings support the hypothesis that combustion-associated pollutants are particularly important in California.
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影响因子：
11.4
作者：
Lough, GC;Schauer, JJ;Weinstein, JP
通讯作者：
Weinstein, JP
影响因子：
5.4
作者：
Schwartz, J
通讯作者：
Schwartz, J
影响因子：
10.4
作者：
Lipsett M;Hurley S;Ostro B
通讯作者：
Ostro B
影响因子：
10.4
作者：
Mar, TF;Norris, GA;Larson, TV
通讯作者：
Larson, TV
DOI：
10.1016/0197-2456(86)90046-2
发表时间：
1986-09-01
期刊：
CONTROLLED CLINICAL TRIALS
影响因子：
--
作者：
DERSIMONIAN, R;LAIRD, N
通讯作者：
LAIRD, N