An implanted 8-channel array coil for high-resolution macaque MRI at 3T.
An implanted 8-channel array coil for high-resolution macaque MRI at 3T.
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DOI：
10.1016/j.neuroimage.2012.05.028
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发表时间：
2012-09
期刊：
影响因子：
5.7
通讯作者：
Vanduffel, W.
中科院分区：
文献类型：
--
作者：
Janssens, T.;Keil, B.;Farivar, R.;McNab, J. A.;Polimeni, J. R.;Gerits, A.;Arsenault, J. T.;Wald, L. L.;Vanduffel, W.
为了提高（功能性）脑成像的灵敏度，构建了8通道接收线圈阵列，并将其植入雄性恒河猴颅骨附近。永久植入物是丙烯酸头柱组件的一部分，只有线圈元素环线被植入。调谐、匹配和前置放大器电路通过一个可移动的外部组件连接。将平行成像的信噪比（SNR）和噪声放大与猕猴功能磁共振成像常规使用的单通道、4通道和8通道外部仅接收线圈进行比较。体内测量显示，与外部线圈相比，植入线圈显著改善了大脑内的信噪比。在覆盖大脑皮层的感兴趣区域内，我们观察到与外部单通道、4通道和8通道线圈相比，信噪比分别增加了5.4倍、3.6倍和3.4倍。在大脑中心，植入阵列与外部线圈相比，分别保持了2.4倍、2.5倍和2.1倍的高信噪比。通过解剖成像、弥散张量成像和脑功能成像来评价该阵列的性能。本研究表明，稳定的植入相控阵线圈可以用于猕猴MRI，从而大大提高解剖、扩散张量和功能成像的空间分辨率。
An 8-channel receive coil array was constructed and implanted adjacent to the skull in a male rhesus monkey in order to improve the sensitivity of (functional) brain imaging. The permanent implant was part of an acrylic headpost assembly and only the coil element loop wires were implanted. The tuning, matching, and preamplifier circuitry was connected via a removable external assembly. Signal-to-noise ratio (SNR) and noise amplification for parallel imaging were compared to a single-, 4-, and 8-channel external receive-only coil routinely used for macaque fMRI. In vivo measurements showed significantly improved SNR within the brain for the implanted versus the external coils. Within a region-of-interest covering the cerebral cortex, we observed a 5.4-, 3.6-fold, and 3.4-fold increase in SNR compared to the external single-, 4-, and 8-channel coil, respectively. In the center of the brain, the implanted array maintained a 2.4×, 2.5×, and 2.1× higher SNR, respectively compared to the external coils. The array performance was evaluated for anatomical, diffusion tensor and functional brain imaging. This study suggests that a stable implanted phased-array coil can be used in macaque MRI to substantially increase the spatial resolution for anatomical, diffusion tensor, and functional imaging.
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影响因子：
3.3
作者：
Khachaturian, Mark H.;Arsenault, John;Ekstrom, Leeland B.;Tuch, David S.;Vanduffel, Wim
通讯作者：
Vanduffel, Wim
早期视觉皮层中额叶信号的自下而上的门控。
DOI：
10.1126/science.1153276
发表时间：
2008-07-18
期刊：
Science (New York, N.Y.)
影响因子：
--
作者：
Ekstrom LB;Roelfsema PR;Arsenault JT;Bonmassar G;Vanduffel W
通讯作者：
Vanduffel W
影响因子：
4.8
作者：
Liu, Xiaoxu;Zhu, Tong;Zhong, Jianhui
通讯作者：
Zhong, Jianhui
DOI：
10.1523/jneurosci.2318-11.2011
发表时间：
2011-09-07
期刊：
The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子：
--
作者：
Mantini D;Gerits A;Nelissen K;Durand JB;Joly O;Simone L;Sawamura H;Wardak C;Orban GA;Buckner RL;Vanduffel W
通讯作者：
Vanduffel W
影响因子：
5.7
作者：
Adluru, Nagesh;Zhang, Hui;Fox, Andrew S.;Shelton, Steven E.;Ennis, Chad M.;Bartosic, Anne M.;Oler, Jonathan A.;Tromp, Do P. M.;Zakszewski, Elizabeth;Gee, James C.;Kalin, Ned H.;Alexander, Andrew L.
通讯作者：
Alexander, Andrew L.