Advances in Chemical Composition, Extraction Techniques, Analytical Methods, and Biological Activity of Astragali Radix.

Advances in Chemical Composition, Extraction Techniques, Analytical Methods, and Biological Activity of Astragali Radix.
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DOI:
10.3390/molecules27031058
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发表时间:
2022-02-04
期刊:
Molecules (Basel, Switzerland)
影响因子:
--
通讯作者:
Chen F
Chen F
中科院分区:
其他
文献类型:
--
作者:
Chang X;Chen X;Guo Y;Gong P;Pei S;Wang D;Wang P;Wang M;Chen F

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黄芪是我国著名的传统中药之一,具有悠久的药用历史和广泛的临床应用。AR含有多种化学成分,可分为以下类别:多糖,皂苷,黄酮类化合物,氨基酸和微量元素。有几种技术来提取这些成分,其中微波辅助,酶,水,超声波和回流提取是最常用的。目前已发展了光谱法、毛细管电泳法和各种色谱法等多种方法来鉴定和分析AR。同时,本文还综述了AR的抗炎、抗氧化、抗肿瘤和抗病毒等生物学活性。以期为更好地开发利用AR提供理论支持。
Astragali Radix (AR) is one of the well-known traditional Chinese medicines with a long history of medical use and a wide range of clinical applications. AR contains a variety of chemical constituents which can be classified into the following categories: polysaccharides, saponins, flavonoids, amino acids, and trace elements. There are several techniques to extract these constituents, of which microwave-assisted, enzymatic, aqueous, ultrasonic and reflux extraction are the most used. Several methods such as spectroscopy, capillary electrophoresis and various chromatographic methods have been developed to identify and analyze AR. Meanwhile, this paper also summarizes the biological activities of AR, such as anti-inflammatory, antioxidant, antitumor and antiviral activities. It is expected to provide theoretical support for the better development and utilization of AR.
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