Antiviral immunity in amphibians.
Antiviral immunity in amphibians.
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DOI:
10.3390/v3112065
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发表时间:
2011-11
期刊:
影响因子:
--
通讯作者:
Robert J
中科院分区:
文献类型:
--
作者:
Chen G;Robert J
Although a variety of virus species can infect amphibians, diseases caused by ranaviruses ([RVs]; Iridoviridae) have become prominent, and are a major concern for biodiversity, agriculture and international trade. The relatively recent and rapid increase in prevalence of RV infections, the wide range of host species infected by RVs, the variability in host resistance among population of the same species and among different developmental stages, all suggest an important involvement of the amphibian immune system. Nevertheless, the roles of the immune system in the etiology of viral diseases in amphibians are still poorly investigated. We review here the current knowledge of antiviral immunity in amphibians, focusing on model species such as the frog Xenopus and the salamander (Ambystoma tigrinum), and on recent progress in generating tools to better understand how host immune defenses control RV infections, pathogenicity, and transmission.
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影响因子:
6.3
作者:
Bancroft, Betsy A.;Baker, Nick J.;Blaustein, Andrew R.
通讯作者:
Blaustein, Andrew R.
影响因子:
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DOI:
10.1111/j.1749-6632.2002.tb04400.x
发表时间:
2002-01-01
期刊:
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