Research on neonatal microbiomes: what neonatologists need to know.
Research on neonatal microbiomes: what neonatologists need to know.
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作者:
Sherman MP;Minnerly J;Curtiss W;Rangwala S;Kelley ST
The aim of this article is to educate neonatal caregivers about metagenomics. This scientific field uses novel and ever changing molecular methods to identify how infants become colonized with microbes after birth. Publications using metagenomics appear infrequently in the neonatal literature because clinicians are unaccustomed with the analytical techniques, data interpretation, and illustration of the results. This review covers those areas. After a brief introduction of neonatal citations forthcoming from metagenomic studies, the following topics are covered: 1) the history of metagenomics, 2) a description of current and emerging instruments used to define microbial populations in human organs, and 3) how extensive databases generated by genome analyzers are examined and presented to readers. Clinicians may feel like they are learning a new language; however, they will appreciate this task is essential to understanding and practicing neonatal medicine in the future.
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影响因子:
4.8
作者:
Hammerstein, Anne F.;Jayasinghe, Lakmal;Bayley, Hagan
通讯作者:
Bayley, Hagan
影响因子:
5.2
作者:
Fortier LC;Sekulovic O
通讯作者:
Sekulovic O
DOI:
10.1093/bioinformatics/btq365
发表时间:
2010-09-15
期刊:
Bioinformatics (Oxford, England)
影响因子:
--
作者:
Balzer S;Malde K;Lanzén A;Sharma A;Jonassen I
通讯作者:
Jonassen I
DOI:
10.1073/pnas.70.12.3581
发表时间:
1973-01-01
影响因子:
11.1
作者:
GILBERT, W;MAXAM, A
通讯作者:
MAXAM, A
DOI:
10.1073/pnas.1002601107
发表时间:
2010-06-29
影响因子:
11.1
作者:
Dominguez-Bello, Maria G.;Costello, Elizabeth K.;Knight, Rob
通讯作者:
Knight, Rob