Human milk pH is associated with fortification, postpartum day, and maternal dietary intake in preterm mother-infant dyads.

Human milk pH is associated with fortification, postpartum day, and maternal dietary intake in preterm mother-infant dyads.
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DOI:
10.1038/s41372-022-01492-5
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发表时间:
2023-01
影响因子:
2.9
通讯作者:
Gregory, Katherine E.
Gregory, Katherine E.
中科院分区:
医学3区
文献类型:
--
作者:
Filatava, Evgenia Jen;Shelly, Colleen E.;Overton, Nicolette E.;Gregas, Matt;Glynn, Robert;Gregory, Katherine E.

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比较早产儿喂养的母乳类型(母乳(母乳)、巴氏灭菌供体母乳(PDHM)、强化母乳和强化PDHM)的pH值。这项观察性研究包括63对妊娠<34周的母婴。采集人乳样本(n = 245),沿着母体因素,进行pH分析。在泌乳过程中分析了乳酸菌的pH值,考虑了强化状态、产后天数和储存条件。牛乳的平均pH值为6.60 ± 0.28,呈微酸性,显著高于其他乳型(p <0.05)。不同的营养强化,产后一天,和产妇的蔬菜/纤维摄入量的pH值。强化状态和产后天数之间存在显著的相互作用;母乳的pH值随着时间的推移而降低,而强化母乳的pH值随着时间的推移而升高。母乳的pH值因类型而异。母乳的pH值与强化状态、产后天数和母亲的蔬菜/纤维摄入量显著相关。
To compare pH of human milk types (mother’s own milk (MOM), pasteurized donor human milk (PDHM), fortified MOM, and fortified PDHM) fed to preterm infants. This observational study consisted of 63 mother-infant dyads <34 weeks gestation. Human milk samples (n=245), along with maternal factors, were collected for pH analysis. pH of MOM was analyzed over the course of lactation accounting for fortification status, postpartum day, and storage conditions. Mean pH of MOM was slightly acidic at 6.60±0.28, which was significantly higher (p<0.05) than other milk types. pH of MOM varied by fortification, postpartum day, and maternal vegetable/fiber intake. There was a significant interaction between fortification status and postpartum day; pH of MOM decreased over time, while pH of fortified MOM increased over time. pH of human milk varied by type. pH of MOM was significantly associated with fortification status, postpartum day, and maternal vegetable/fiber intake.
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