Siri of the cell: what biology could learn from the iPhone.

Siri of the cell: what biology could learn from the iPhone.
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DOI:
10.1016/j.cell.2014.03.009
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发表时间:
2014-04-24
期刊:
影响因子:
64.5
通讯作者:
Ideker T
Ideker T
中科院分区:
生物学1区
文献类型:
--
作者:
Carvunis AR;Ideker T

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现代基因组学在绘制基因和基因网络方面非常有效,但如何将这些图谱转化为细胞的预测模型仍不清楚。计算机科学的最新进展,如Siri等智能代理,激发了一种从网络到多尺度模型的方法,能够预测一系列细胞表型并回答生物学问题。
Modern genomics is very efficient at mapping genes and gene networks, but how to transform these maps into predictive models of the cell remains unclear. Recent progress in computer science, embodied by intelligent agents such as Siri, inspires an approach for moving from networks to multiscale models able to predict a range of cellular phenotypes and answer biological questions.
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