Mechanisms for widespread hippocampal involvement in cognition.
Mechanisms for widespread hippocampal involvement in cognition.
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DOI：
10.1037/a0034461
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发表时间：
2013-11
影响因子：
4.1
通讯作者：
Turk-Browne, Nicholas B.
中科院分区：
文献类型：
--
作者：
Shohamy, Daphna;Turk-Browne, Nicholas B.
人脑中典型的记忆系统——海马体和周围的内侧颞叶（MTL）——通常被视为形成意识或陈述性记忆的模块。然而，越来越多的证据表明，海马体在记忆和认知中发挥着更广泛的作用，并且将记忆组织成严格专用系统的理论可能需要更新。我们首先考虑海马体在陈述性记忆中特殊作用的历史证据。然后，我们根据我们实验室的平行研究描述了激发这个特殊部分的偶然遭遇，该研究表明海马体对陈述性记忆之外的认知做出了更普遍的贡献。最后，我们开发了一个理论框架，描述了海马体如何与其他大脑系统和认知过程相互作用的两种一般机制：记忆调节假说，其中海马体中的助记符表示调节其他系统的操作，以及自适应功能假说，其中海马体中的专门计算被招募为助记符和非助记符功能的组成部分。这一框架与一种新兴观点是一致的，即认知心理学和神经科学发现的最肥沃的土壤位于传统上孤立研究的心智和大脑部分之间的界面。
The quintessential memory system in the human brain — the hippocampus and surrounding medial temporal lobe (MTL) — is often treated as a module for the formation of conscious, or declarative memories. However, growing evidence suggests that the hippocampus plays a broader role in memory and cognition and that theories organizing memory into strictly dedicated systems may need to be updated. We first consider the historical evidence for the specialized role of the hippocampus in declarative memory. Then, we describe the serendipitous encounter that motivated this special section, based on parallel research from our labs that suggested a more pervasive contribution of the hippocampus to cognition beyond declarative memory. Finally, we develop a theoretical framework that describes two general mechanisms for how the hippocampus interacts with other brain systems and cognitive processes: the Memory Modulation Hypothesis, in which mnemonic representations in the hippocampus modulate the operation of other systems, and the Adaptive Function Hypothesis, in which specialized computations in the hippocampus are recruited as a component of both mnemonic and non-mnemonic functions. This framework is consistent with an emerging view that the most fertile ground for discovery in cognitive psychology and neuroscience lies at the interface between parts of the mind and brain that have traditionally been studied in isolation.
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影响因子：
7.2
作者：
Aslin RN;Newport EL
通讯作者：
Newport EL
影响因子：
2.9
作者：
Addis DR;Schacter DL
通讯作者：
Schacter DL
影响因子：
3.7
作者：
Durrant, Simon J.;Cairney, Scott A.;Lewis, Penelope A.
通讯作者：
Lewis, Penelope A.
影响因子：
25
作者：
Bonnevie, Tora;Dunn, Benjamin;Moser, May-Britt
通讯作者：
Moser, May-Britt
DOI：
10.1073/pnas.94.13.7109
发表时间：
1997-06-24
影响因子：
11.1
作者：
Dusek, JA;Eichenbaum, H
通讯作者：
Eichenbaum, H