Metaproteomics: harnessing the power of high performance mass spectrometry to identify the suite of proteins that control metabolic activities in microbial communities.

Metaproteomics: harnessing the power of high performance mass spectrometry to identify the suite of proteins that control metabolic activities in microbial communities.
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元蛋白质组学:利用高性能质谱的力量来识别控制微生物群落中代谢活性的蛋白质套件。

DOI:
10.1021/ac303053e
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发表时间:
2013-05-07
影响因子:
7.4
通讯作者:
Giannone RJ
Giannone RJ
中科院分区:
化学1区
文献类型:
--
作者:
Hettich RL;Pan C;Chourey K;Giannone RJ

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许多不同微生物的广泛基因组信息的可用性,包括来自环境样品的混合群落中的不可培养的物种,通过提供访问基因组、转录组和蛋白质组信息的手段,使系统生物学询问成为可能。为此,元蛋白质组学利用高性能质谱的能力,对环境样品中微生物群落表达的全套蛋白质进行广泛表征。
The availability of extensive genome information for many different microbes, including unculturable species in mixed communities from environmental samples, has enabled systems-biology interrogation by providing a means to access genomic, transcriptomic, and proteomic information. To this end, metaproteomics exploits the power of high performance mass spectrometry for extensive characterization of the complete suite of proteins expressed by a microbial community in an environmental sample.
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