Changing partners: moving from non-homologous to homologous centromere pairing in meiosis.
Changing partners: moving from non-homologous to homologous centromere pairing in meiosis.
复制标题
DOI：
10.1016/j.tig.2008.08.006
复制
发表时间：
2008-11
影响因子：
11.4
通讯作者：
Dawson, Dean S.
中科院分区：
文献类型：
--
作者：
Stewart, Mara N.;Dawson, Dean S.
在过去的三十年里，关于减数分裂早期细胞中着丝粒配对的报道时有发生。最近的实验表明，早期的着丝粒配对发生在非同源的着丝粒之间。随着减数分裂的进行，着丝粒改变伴侣，变成同源配对。对这些后来的着丝粒对的研究表明，成对的同源着丝粒是主动相关的，而不是被动地并排定位。在小鼠、小麦和酵母等多种生物体中都观察到了减数分裂中的着丝粒配对现象，这表明减数分裂早期的非同源着丝粒配对和减数分裂后期活跃的同源着丝粒配对可能是减数分裂染色体行为的主题。此外，这种配对可能在介导影响减数分裂分离保真度的染色体组织或结构中具有先前未被认识的作用。
Reports of centromere pairing in early meiotic cells have appeared sporadically over the past thirty years. Recent experiments demonstrate that early centromere pairing occurs between non-homologous centromeres. As meiosis proceeds, centromeres change partners, becoming arranged in homologous pairs. Investigations of these later centromere pairs indicate that paired homologous centromeres are actively associated rather than positioned passively, side-by-side. Meiotic centromere pairing has been observed in organisms as diverse as mice, wheat and yeast, indicating that non-homologous centromere pairing in early meiosis and active homologous centromere pairing in later meiosis might be themes in meiotic chromosome behavior. Moreover, such pairing could have previously unrecognized roles in mediating chromosome organization or architecture that impact meiotic segregation fidelity.
登录
查看更多内容
影响因子：
1.6
作者：
CHURCH, K;MOENS, PB
通讯作者：
MOENS, PB
影响因子：
64.5
作者：
Chikashige, Y;Tsutsumi, C;Hiraoka, Y
通讯作者：
Hiraoka, Y
影响因子：
64.5
作者：
Conrad, Michael N.;Lee, Chih-Ying;Dresser, Michael E.
通讯作者：
Dresser, Michael E.
影响因子：
1.6
作者：
BRINKLEY, BR;BRENNER, SL;VALDIVIA, MM
通讯作者：
VALDIVIA, MM
影响因子：
11.8
作者：
Ding, DQ;Yamamoto, A;Hiraoka, Y
通讯作者：
Hiraoka, Y