The Mouse Superior Colliculus: An Emerging Model for Studying Circuit Formation and Function.

The Mouse Superior Colliculus: An Emerging Model for Studying Circuit Formation and Function.
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DOI:
10.3389/fncir.2018.00010
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发表时间:
2018
影响因子:
3.5
通讯作者:
Feldheim DA
Feldheim DA
中科院分区:
医学3区
文献类型:
--
作者:
Ito S;Feldheim DA

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上级丘(SC)是一个中脑区域,视觉,听觉和体感信息整合启动运动命令。SC在小鼠的视觉信息处理中起着核心作用;它接收来自85%至90%的视网膜神经节细胞(RGC)的投射。虽然小鼠SC一直是用于研究视网膜定位图形成的长期模型,但小鼠分子遗传技术,大规模生理记录和SC依赖性视觉行为测定的许多技术进步使小鼠成为了解电路和行为之间关系的更理想模型。
The superior colliculus (SC) is a midbrain area where visual, auditory and somatosensory information are integrated to initiate motor commands. The SC plays a central role in visual information processing in the mouse; it receives projections from 85% to 90% of the retinal ganglion cells (RGCs). While the mouse SC has been a long-standing model used to study retinotopic map formation, a number of technological advances in mouse molecular genetic techniques, large-scale physiological recordings and SC-dependent visual behavioral assays have made the mouse an even more ideal model to understand the relationship between circuitry and behavior.
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