Repeatability and Comparability of Retinal Blood Vessel Caliber Measurements by OCTA.
Repeatability and Comparability of Retinal Blood Vessel Caliber Measurements by OCTA.
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DOI：
10.3390/vision7030048
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发表时间：
2023-07-03
期刊：
影响因子：
--
通讯作者：
Saeedi O
中科院分区：
文献类型：
--
作者：
Tsai J;Asanad S;Whiting M;Zhang X;Magder L;Saeedi O
背景：研究光学相干断层扫描血管造影（OCTA）测量血管口径的可重复性。方法：对28例（47眼）视神经乳头和黄斑进行OCTA检查。两名独立的蒙面分级者测量视神经乳头和黄斑的连续图像的血管口径。确定平均血管宽度以及分级者和图像之间的变异性。结果：84张OCTA图像的420条血管共8400个测量值被纳入分析。总体而言，年级间协议是优秀的（ICC 0.90）。所有重复OCTA图像的变异系数（CoV）为0.10。青光眼严重程度越高、年龄越大、黄斑位置和糖尿病诊断与血管越细相关（p < 0.05）。与黄斑（0.15）相比，乳头周围区域（0.07）中的CoV更高。除了黄斑（ICC = 0.72）外，所有亚组的ICC均较高。结论：总体而言，OCTA测量血管口径的重复性高，变异性低。黄斑血管的测量存在较大的变异性，可能是由于获取较小黄斑血管的准确血管宽度的技术限制。
Background: To investigate the repeatability in vessel caliber measurements by optical coherence tomography angiography (OCTA). Methods: In this prospective study, 28 patients (47 eyes) underwent sequential OCTA imaging of the optic nerve head and macula. Two independent masked graders measured vessel caliber for sequential images of the optic nerve head and macula. The average vessel width was determined and variability between graders and images. Results: A total of 8400 measurements of 420 vessels from 84 OCTA images were included in the analysis. Overall, inter-grader agreement was excellent (ICC 0.90). The coefficient of variation (CoV) for all repeated OCTA images was 0.10. Greater glaucoma severity, older age, macular location, and diagnosis of diabetes were associated with thinner vessels (p < 0.05). CoV was higher in the peripapillary region (0.07) as compared to the macula (0.15). ICC was high for all subgroups except for the macula (ICC = 0.72). Conclusions: Overall, the repeatability of vessel caliber measurements by OCTA was high and variability low. There was greater variability in the measurement of macular vessels, possibly due to technical limitations in acquiring accurate vessel widths for smaller macular vessels.
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DOI：
10.3390/diagnostics12081908
发表时间：
2022-08-07
期刊：
Diagnostics (Basel, Switzerland)
影响因子：
--
作者：
通讯作者：
--
影响因子：
3.7
作者：
Gołębiewska J;Olechowski A;Wysocka-Mincewicz M;Odrobina D;Baszyńska-Wilk M;Groszek A;Szalecki M;Hautz W
通讯作者：
Hautz W
影响因子：
3.4
作者：
Bedggood P;Metha A
通讯作者：
Metha A
影响因子：
3.1
作者：
Battu R;Dabir S;Khanna A;Kumar AK;Sinha Roy A
通讯作者：
Sinha Roy A
影响因子：
4.4
作者：
Fondi, Klemens;Aschinger, Gerold C.;Schmetterer, Leopold
通讯作者：
Schmetterer, Leopold